SynthesisHealth and quality of life outcomes2019
Quality of life, symptoms, and sleep quality of elderly with end-stage renal disease receiving conservative management: a systematic review.
Synthesis in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Policy strategies to enhance uptake of conservative kidney management in advanced chronic kidney disease: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Sleep disturbances in adults with chronic kidney disease: an umbrella review.Journal of nephrology · 2025Pooled it
- Long-term Outcomes Among Patients With Advanced Kidney Disease Who Forgo Maintenance Dialysis: A Systematic Review.JAMA network open · 2022Pooled it
- Decisional Conflict and Patient Experiences in Dialysis Treatment Decision-Making: A Mixed-Methods Study in a Portuguese Cohort.Healthcare (Basel, Switzerland) · 2026Article
- End-of-life of conservative kidney management in older CKD patients undergoing comprehensive geriatric assessment.Clinical and experimental nephrology · 2026Article
- Effect of a Spiritual Care Program on Treatment Adherence and Sleep Quality in Hemodialysis Patients: A Cluster-Randomized Clinical Trial.Health science reports · 2025Article
- Machine learning to predict postdialysis fatigue in patients undergoing hemodialysis.Renal failure · 2025Article
- Effect of periodic nursing interventions on improving compliance behavior and health status in long-term Hemodialysis patients.Pakistan journal of medical sciences · 2024Article
- The impact of quality of life on the survival of elderly patients with end-stage renal disease: a prospective multicenter cohort study in Korea.Clinical kidney journal · 2024Article
- Nephrologists' perspectives and experiences with hospice among older adults with end-stage kidney disease.Journal of the American Geriatrics Society · 2024Article
- Article
- Economic evaluation of dialysis and comprehensive conservative care for chronic kidney disease using the ICECAP-O and EQ-5D-5L; a comparison of evaluation instruments.Cost effectiveness and resource allocation : C/E · 2023Article
- Five-Year Symptom Trajectories in Nondialysis-Dependent CKD Patients.Clinical journal of the American Society of Nephrology : CJASN · 2022Article
- Effects of Psychotherapy on Quality of Life in End-stage Renal Disease Patients: A Systematic Review with Meta-analysis.Oman medical journal · 2022Review
- Sexuality in Kidney Transplant Recipients: A Qualitative Study.Healthcare (Basel, Switzerland) · 2021Article
- Communication principles and practices for making shared decisions about renal replacement therapy: a review of the literature.Current opinion in nephrology and hypertension · 2021Review
- The Prepare for Kidney Care Study: prepare for renal dialysis versus responsive management in advanced chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Review
- Musculoskeletal Disorders and Associated Factors Among Patients with Chronic Kidney Disease Attending at Saint Paul Hospital, Addis Ababa, Ethiopia.International journal of nephrology and renovascular disease · 2021Article
- Correlation of sociodemographic profiles with psychological problems among hospitalized patients receiving unplanned hemodialysis.Renal failure · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlder patients with end-stage renal disease (ESRD) have experienced diminished quality of life and debilitating symptoms. Conservative management may be a potential treatment option. Currently, limited studies have been conducted about the main outcome of conservative management, including quality of life, symptoms and sleep quality. The aim of this systematic review was to examine the quality of life, symptoms and sleep quality of elderly patients with ESRD undergoing conservative management.
methodsEvidence-based medicine database (JBI and Cochrane) and original literature database (PubMed, Medline, EMbase, Web of Science) were searched up to March 12, 2018. The quality of included papers was evaluated with the Newcastle-Ottawa Scale.
resultsEight studies met the inclusion criteria. The total of 1229 patients were involved with an average age of 60.6 ~ 82 years. Patients choosing conservative management were older and more functionally impaired compared to those opting for dialysis. 55% patients undergoing conservative management had stable or improved quality of life and symptoms in prospective cohort study. However, the results revealed that there were no significant differences in quality of life and symptom between conservative management and renal replacement therapy. Only one study assessed quality of life of older patients using SF-36, with a lower score in physical health subscale of conservative management patients than those of renal replacement therapy. Although more than 40% of the patients had poor sleep quality, no significant difference was found between conservative management and renal replacement therapy. Sleep disorders were associated with fatigue and other symptoms.
conclusionsAlthough there is a limited literature, conservative management is likely to improve quality of life and alleviate symptoms of end-stage renal disease patients with considerable clinical implications mainly in elderly patients. Future study should pay more attention to the various treatment outcomes of conservative management, providing abundant evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.