Evidence map›Paper›PMID 31053061›Full record

ArticleBMC genomics2019

Consequences of breed formation on patterns of genomic diversity and differentiation: the case of highly diverse peripheral Iberian cattle.

Rute R da Fonseca, Irene Ureña, Sandra Afonso, Ana Elisabete Pires, Emil Jørsboe, Lounès Chikhi, Catarina Ginja

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Rute R da FonsecaCenter for Macroecology, Evolution and Climate, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark. rfonseca@snm.ku.dk.ORCID http://orcid.org/0000-0002-2805-4698
Irene UreñaCIBIO-InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal.
Sandra AfonsoCIBIO-InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal.
Ana Elisabete PiresCIBIO-InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal.
Emil JørsboeThe Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Lounès ChikhiLaboratoire Évolution & Diversité Biologique (EDB UMR 5174), Université de Toulouse Midi-Pyrénées, CNRS, IRD, UPS. 118 route de Narbonne, Bat 4R1, 31062, Toulouse cedex 9, France.
Catarina GinjaCIBIO-InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal. catarinaginja@cibio.up.pt.
Universidade do Porto · PTUniversity of Copenhagen · DKCentre National de la Recherche Scientifique · FR

Funding

Monoterpenes in Cancer Prevention and TherapyR03CA112653 · NCI · WEST VIRGINIA UNIVERSITY · PI VINCENT, TIMOTHY SCOTT · 2004 to 2005
$146k
Danmarks Grundforskningsfond DNRF96Fundação para a Ciência e a Tecnologia IF/00866/2014Fundação para a Ciência e a Tecnologia PTDC/CVTLIV/2827/2014Fundação para a Ciência e a Tecnologia SFRH/BPD/112653/2015Villum Fonden VKR023446
6 · The paper itself

Abstract

backgroundIberian primitive breeds exhibit a remarkable phenotypic diversity over a very limited geographical space. While genomic data are accumulating for most commercial cattle, it is still lacking for these primitive breeds. Whole genome data is key to understand the consequences of historic breed formation and the putative role of earlier admixture events in the observed diversity patterns.

resultsWe sequenced 48 genomes belonging to eight Iberian native breeds and found that the individual breeds are genetically very distinct with F

conclusionsOur results show that an overall complex history of admixture resulted in unexpectedly high levels of genomic diversity for breeds with seemingly limited geographic ranges that are distantly located from the main domestication center for taurine cattle in the Near East. This is likely to result from a combination of trading traditions and breeding practices in Mediterranean countries. We also found that the levels of differentiation of autosomes vs sex chromosomes across all studied taurine and indicine breeds are likely to have been affected by widespread breeding practices associated with male-biased gene flow.

Indexed as

BreedingGenetics, PopulationGenetic VariationGenomeAnimalsCattleChromosomes, MammalianDNA, MitochondrialEuropeFemaleGene FlowGenomicsGenotypeHaplotypesMaleMicrosatellite RepeatsDNA, MitochondrialAnimal breedingCattle genomesGenetic differentiationGenomic diversityIberiaNative breedspopulation structureSex chromosome diversity

Identifiers

PMID31053061
PMCPMC6500009
OpenAlexW2899978633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.