Evidence map›Paper›PMID 31052833›Full record

ArticleOptics express2019

Fluorescent coherent diffractive imaging with accelerating light sheets.

Jeffrey J Field, Jeff A Squier, Randy A Bartels

Abstract read
In one paragraph

Article in Optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeffrey J Field
Jeff A Squier
Randy A Bartels

Funding

Deep-tissue super-resolved microscopy with multiphoton spatial frequency-modulated imaging (MP-SPIFI)R21MH117786 · NIMH · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
Unrestricted super-resolution imaging deep in tissues through scattering immune spatial frequency modulated imagingR21EB025389 · NIBIB · COLORADO STATE UNIVERSITY · PI BARTELS, RANDY A. · 2018 to 2019
$362k
NIBIB NIH HHS R21 EB025389NIMH NIH HHS R21 MH117786
6 · The paper itself

Abstract

Fluorescence microscopy is a powerful method for producing high fidelity images with high spatial resolution, particularly in the biological sciences. We recently introduced coherent holographic image reconstruction by phase transfer (CHIRPT), a single-pixel imaging method that significantly improves the depth of field in fluorescence microscopy and enables holographic refocusing of fluorescent light. Here we demonstrate that by installing a confocal slit conjugate to the illuminating light sheets used in CHIRPT, out-of-focus light is rejected, thus improving lateral spatial resolution and rejecting noise from out-of-focus fluorescent light. Confocal CHIRPT is demonstrated and fully modeled. Finally, we explore the use of beam shaping and point-spread-function engineering to enable holographic single-lens light-sheet microscopy with single-pixel detection.

Identifiers

PMID31052833
PMCPMC6825600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.