Evidence map›Paper›PMID 31052578›Full record

ArticleGenes2019

Physiological and Genetic Dissection of Sucrose Inputs to the

Koumis Philippou, James Ronald, Alfredo Sánchez-Villarreal, Amanda M Davis, Seth J Davis

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Koumis PhilippouDepartment of Plant Developmental Biology, Max-Planck Institute for Plant Breeding Research, Cologne D50829, Germany. iakk2003@yahoo.gr.
James RonaldDepartment of Biology, University of York, York, YO10 5DD, UK. jar563@york.ac.uk.
Alfredo Sánchez-VillarrealDepartment of Plant Developmental Biology, Max-Planck Institute for Plant Breeding Research, Cologne D50829, Germany. asanchezv@colpos.mx.
Amanda M DavisDepartment of Plant Developmental Biology, Max-Planck Institute for Plant Breeding Research, Cologne D50829, Germany. amanda.davis@york.ac.uk.
Seth J DavisDepartment of Plant Developmental Biology, Max-Planck Institute for Plant Breeding Research, Cologne D50829, Germany. seth.davis@york.ac.uk.
Max Planck Institute for Plant Breeding Research · DEAutonomous University of Campeche · MXUniversity of York · GB

Funding

Biotechnology and Biological Sciences Research Council BBB/M000435/1Biotechnology and Biological Sciences Research Council BB/N018540/1
6 · The paper itself

Abstract

Circadian rhythms allow an organism to synchronize internal physiological responses to the external environment. Perception of external signals such as light and temperature are critical in the entrainment of the oscillator. However, sugar can also act as an entraining signal. In this work, we have confirmed that sucrose accelerates the circadian period, but this observed effect is dependent on the reporter gene used. This observed response was dependent on sucrose being available during free-running conditions. If sucrose was applied during entrainment, the circadian period was only temporally accelerated, if any effect was observed at all. We also found that sucrose acts to stabilize the robustness of the circadian period under red light or blue light, in addition to its previously described role in stabilizing the robustness of rhythms in the dark. Finally, we also found that CCA1 is required for both a short- and long-term response of the circadian oscillator to sucrose, while LHY acts to attenuate the effects of sucrose on circadian period. Together, this work highlights new pathways for how sucrose could be signaling to the oscillator and reveals further functional separation of CCA1 and LHY.

Indexed as

ArabidopsisArabidopsis ProteinsCircadian RhythmDNA-Binding ProteinsGene Expression Regulation, PlantLightSucroseTranscription FactorsArabidopsis ProteinsCCA1 protein, ArabidopsisDNA-Binding ProteinsLHY protein, ArabidopsisSucroseTranscription FactorsCCA1circadian rhythmLHYpathwaysucrose

Identifiers

PMID31052578
PMCPMC6563356
OpenAlexW2943611165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.