Evidence map›Paper›PMID 31052566›Full record

ReviewAntibiotics (Basel, Switzerland)2019

Antibiotic Prophylaxis on Third Molar Extraction: Systematic Review of Recent Data.

Gabriele Cervino, Marco Cicciù, Antonio Biondi, Salvatore Bocchieri, Alan Scott Herford, Luigi Laino, Luca Fiorillo

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05027893 (Efficacy of the Application of Moxifloxacin and Cefixime in Reduction of Inflammatory Sequelae and Complications After Mandibular Third Molar Surgery), which is not on this map. Cited by 46 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 6 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05027893 naunknown statusnot on this map

Efficacy of the Application of Moxifloxacin and Cefixime in Reduction of Inflammatory Sequelae and Complications After Mandibular Third Molar Surgery

TypeinterventionalSponsorUniversity of Novi SadRan2019 to 2023Enrolled157ConditionsPostoperative Complications, Antibiotic Reaction, Antibiotic Side Effect, Antibiotic Resistant InfectionArmsMoxifloxacin 400 mg Oral Tablet, Cefixime 400 mg Oral Tablet, Placebo
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 6 syntheses or guidelines pooled it, 96 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Gabriele CervinoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, 98100 Messina, Italy. gcervino@unime.it.ORCID 0000-0003-4619-4691
Marco CicciùDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, 98100 Messina, Italy. mcicciu@unime.it.ORCID 0000-0003-2311-9728
Antonio BiondiDepartment of General Surgery and Medical Surgery Specialties, University of Catania, 95100 Catania, Italy. abiondi@unict.it.
Salvatore BocchieriDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, 98100 Messina, Italy. salvo.bocchieri@gmail.com.
Alan Scott HerfordDepartment of Maxillofacial Surgery, Loma Linda University, Loma Linda, CA 92354, USA. aherford@llu.edu.
Luigi LainoMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli", 80121 Naples, Italy. luigi.laino@unicampania.it.
Luca FiorilloDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, School of Dentistry, University of Messina, 98100 Messina, Italy. lfiorillo@unime.it.ORCID 0000-0003-0335-4165
University of Messina · ITLoma Linda University · USUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this paper was to highlight the most widely antibiotic protocols applied to the dental field, especially in the surgical treatment of impacted wisdom teeth. Once these protocols were screened, all the possible advantages or disadvantages for each drug and each posology were recorded in this review. In recent years, the need to use these protocols has been debated in the literature. The data obtained by this review underlined how antibiotic protocols applied to oral surgery treatments only included surgeries performed on patients who did not present other systemic pathologies. The first literature review obtained 140 results, and then after the application of the inclusion criteria, 12 papers were selected. The results showed that the most commonly used protocol involved the use of penicillin and clavulanate, obtaining safe clinical and prophylactic results in the management of infections. This widely used protocol seems to guarantee high predictability and safety. The presented review highlights the current possibility of antibiotic resistance affecting patients due to drug misuse. Further clinical studies are required to state specific guidelines; however, oral surgeons involved in third molar surgery should evaluate the local and general health conditions of the patients before suggesting any drug measures for patients.

Indexed as

antibioticextractionoral surgeryprophylaxisthird molar

Identifiers

PMID31052566
PMCPMC6627726
OpenAlexW2943721847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.