ArticleInternational journal of molecular sciences2019
Inflammatory, Serological and Vascular Determinants of Cardiovascular Disease in Systemic Lupus Erythematosus Patients.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Burden of incident cardiovascular events in giant cell arteritis using data from a nationwide French cohort.Scientific reports · 2026Article
- Subclinical coronary artery calcification is associated with future inflammatory conditions in the multi-ethnic study of atherosclerosis.American journal of preventive cardiology · 2026Article
- Artificial intelligence-based cardiovascular/stroke risk stratification in women affected by autoimmune disorders: a narrative survey.Rheumatology international · 2025Review
- Comparison of Metabolic Syndrome, Autoimmune and Viral Distinctive Inflammatory Related Conditions as Affected by Body Mass Index.Journal of clinical medicine · 2024Article
- Phylloquinone improves endothelial function, inhibits cellular senescence, and vascular inflammation.GeroScience · 2024Article
- Fourier transform infrared spectroscopy and machine learning for Porphyromonas gingivalis detection in oral bacteria.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024Article
- Assessment of Arterial Stiffness and Biochemical Markers in Systemic Lupus Erythematosus in the Diagnosis of Subclinical Atherosclerosis.Journal of personalized medicine · 2024Article
- Cardiovascular Disease in Diabetes and Chronic Kidney Disease.Journal of clinical medicine · 2023Review
- The Ketogenic Diet and Cardiovascular Diseases.Nutrients · 2023Review
- Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review.Nutrients · 2023Review
- Disturbances of circadian profile and blood pressure control in patients with systemic lupus erythematosus without overt heart disease.Postepy dermatologii i alergologii · 2022Article
- Serum amyloid A-to-albumin ratio as a potential biomarker to predict the activity, severity, and poor prognosis of systemic lupus erythematosus.Journal of clinical laboratory analysis · 2022Article
- Cardiac Magnetic Resonance in Rheumatology to Detect Cardiac Involvement Since Early and Pre-clinical Stages of the Autoimmune Diseases: A Narrative Review.Frontiers in cardiovascular medicine · 2022Review
- Inflammatory Bowel Disease Does Not Impact Mortality but Increases Length of Hospitalization in Patients with Acute Myocardial Infarction.Digestive diseases and sciences · 2021Observational
- Emerging role of interleukin-13 in cardiovascular diseases: A ray of hope.Journal of cellular and molecular medicine · 2021Review
- Aortic adventitial thickness as a marker of aortic atherosclerosis, vascular stiffness, and vessel remodeling in systemic lupus erythematosus.Clinical rheumatology · 2021Article
- The Potential of Hydrogen Sulfide Donors in Treating Cardiovascular Diseases.International journal of molecular sciences · 2021Review
- Metabolic Control of Autoimmunity and Tissue Inflammation in Rheumatoid Arthritis.Frontiers in immunology · 2021Review
- Cross-Sectional Analysis of the Association between Periodontitis and Cardiovascular Disease Using the Korean Genome and Epidemiology Study Data.International journal of environmental research and public health · 2020Article
- Inflammation and Cardiovascular Diseases: The Most Recent Findings.International journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
aimSystemic lupus erythematosus (SLE) is associated with increased risk of cardiovascular disease (CVD). Among many mechanisms, accelerated atherosclerosis, endothelial dysfunction, and hypercoagulability play a main role. Here, we investigate whether inflammatory, serological and clinical markers of SLE determine and correlate with arterial stiffness in SLE patients. MATERIALS AND
methodsRoutine blood samples, inflammatory mediators, specific antibodies, and 24 h proteinuria were measured in 43 SLE patients and 43 age and sex-matched controls using routine laboratory assays. We also assessed arterial stiffness by measuring radial artery applanation tonometry-derived augmentation index (AI), normalized AI (AIx@75), aortic pulse pressure, central systolic, diastolic and peripheral blood pressure.
resultsSLE patients showed a significantly greater arterial stiffness vs. controls, as demonstrated by the significantly higher AIx@75 and aortic pulse pressure. Interestingly, regression analysis showed that age, systolic pulse pressure, inflammatory markers (erythrocyte sedimentation rate and C-reactive protein), daily dose of glucocorticoids, and cumulative organ damage positively correlated with arterial stiffness.
conclusionsSLE patients show increased arterial stiffness which correlates with markers of inflammation, that is involved in early alterations in arterial walls. Applanation tonometry can be used to screen SLE patients for subclinical vascular damage to implement prevention strategies for CVD.
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