Evidence map›Paper›PMID 31052191›Full record

ArticleInternational journal of molecular sciences2019

A Survey on Tubulin and Arginine Methyltransferase Families Sheds Light on

Maria Antonietta Ragusa, Aldo Nicosia, Salvatore Costa, Caterina Casano, Fabrizio Gianguzza

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Microorganisms · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria Antonietta RagusaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16, Palermo, 90128 Sicily, Italy.. maria.ragusa@unipa.it.
Aldo NicosiaNational Research Council-Istituto per lo studio degli impatti Antropici e Sostenibilità in ambiente marino (IAS-CNR), Laboratory of Molecular Ecology and Biotechnology, Detached Unit of Capo Granitola, Via del mare, Torretta Granitola (TP), 91021 Sicily, Italy. aldo.nicosia@cnr.it.ORCID 0000-0002-1013-2862
Salvatore CostaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16, Palermo, 90128 Sicily, Italy.. salvatore.costa@unipa.it.ORCID 0000-0003-2798-4401
Caterina CasanoDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16, Palermo, 90128 Sicily, Italy.. casanocaterina@gmail.com.
Fabrizio GianguzzaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16, Palermo, 90128 Sicily, Italy.. fabrizio.gianguzza@unipa.it.
University of Palermo · ITInstitute for Coastal Marine Environment · IT

Funding

University of Palermo B74G13000040001
6 · The paper itself

Abstract

Tubulins and microtubules (MTs) represent targets for taxane-based chemotherapy. To date, several lines of evidence suggest that effectiveness of compounds binding tubulin often relies on different post-translational modifications on tubulins. Among them, methylation was recently associated to drug resistance mechanisms impairing taxanes binding. The sea urchin is recognized as a research model in several fields including fertilization, embryo development and toxicology. To date, some α- and β-tubulin genes have been identified in

Indexed as

AnimalsCytostatic AgentsEmbryo, NonmammalianIntracellular Signaling Peptides and ProteinsMethylationProtein-Arginine N-MethyltransferasesProtein Processing, Post-TranslationalSea UrchinsToxicity TestsTubulinTubulin ModulatorsCytostatic AgentsIntracellular Signaling Peptides and ProteinsPRMT2 protein, humanProtein-Arginine N-MethyltransferasesTubulinTubulin Modulatorsarginine methylationechinodermspost-translational modificationPRMTsea urchintubulin

Identifiers

PMID31052191
PMCPMC6539552
OpenAlexW2943697481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.