Evidence map›Paper›PMID 31052189›Full record

ArticleToxins2019

Proteomic Analysis of Human Blister Fluids Following Envenomation by Three Snake Species in India: Differential Markers for Venom Mechanisms of Action.

Jéssica K A Macêdo, Joseph K Joseph, Jaideep Menon, Teresa Escalante, Alexandra Rucavado, José María Gutiérrez, Jay W Fox

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Thromboinflammatory complications ofFrontiers in immunology · 2025
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  7. Crosstalk of Inflammation and Coagulation inInternational journal of molecular sciences · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Observation ofToxins · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Jéssica K A MacêdoDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, School of Medicine, Charlottesville, VA 22908-734, USA. macedojka@gmail.com.ORCID 0000-0003-1234-7071
Joseph K JosephLittle Flower Hospital, Angamaly 683572, India. drjosephkjoseph@gmail.com.
Jaideep MenonSree Naryana Institute of Medical Science, Kerala 683594, India. menon7jc@gmail.com.
Teresa EscalanteInstituto Clodomiro Picado, School of Microbiology, University of Costa Rica, San José 11501-2060, Costa Rica. teresa.escalante@ucr.ac.cr.
Alexandra RucavadoInstituto Clodomiro Picado, School of Microbiology, University of Costa Rica, San José 11501-2060, Costa Rica. alexandra.rucavado@ucr.ac.cr.
José María GutiérrezInstituto Clodomiro Picado, School of Microbiology, University of Costa Rica, San José 11501-2060, Costa Rica. jose.gutierrez@ucr.ac.cr.ORCID 0000-0001-8385-3081
Jay W FoxDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, School of Medicine, Charlottesville, VA 22908-734, USA. jwf8x@virginia.edu.
Universidad de Costa Rica · CRLittle Flower Hospital & Research Centre · INUniversidade de Brasília · BRUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin blistering as a result of snakebite envenomation is characteristic of some bites, however little is known regarding the mechanism of blister formation or the composition of the blister fluid. In order to investigate if blister fluid proteomes from humans suffering snakebite envenomation could provide insights on the pathophysiology of these skin alterations, blister fluid was collected from six patients upon presentation at a clinic in India bitten by three species of snakes,

Indexed as

BlisterSnake BitesAdultAgedAnimalsChild, PreschoolElapid VenomsFemaleHumansIndiaInfantMaleMiddle AgedProteomeProteomicsReptilian ProteinsElapid VenomsProteomeReptilian ProteinsViper Venomsblister fluidextracellular matrixinflammationproteomicssnake venomsnake venom metalloproteinases (SVMP)wound exudate

Identifiers

PMID31052189
PMCPMC6563188
OpenAlexW2943077230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.