Evidence map›Paper›PMID 31052187›Full record

ArticleInternational journal of molecular sciences2019

High-Amylose Maize, Potato, and Butyrylated Starch Modulate Large Intestinal Fermentation, Microbial Composition, and Oncogenic miRNA Expression in Rats Fed A High-Protein Meat Diet.

Tina S Nielsen, Zach Bendiks, Bo Thomsen, Matthew E Wright, Peter K Theil, Benjamin L Scherer, Maria L Marco

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

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  4. Anti-Inflammatory and Anticancer Potential ofJournal of inflammation research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Tina S NielsenDepartment of Animal Science, Aarhus University, DK-8830 Tjele, Denmark. TinaS.Nielsen@anis.au.dk.ORCID 0000-0003-0541-4387
Zach BendiksDepartment of Food Science & Technology, University of California, Davis, CA 95616, USA. zabendiks@ucdavis.edu.
Bo ThomsenDepartment of Molecular Biology & Genetics, Aarhus University, DK-8000 Aarhus C, Denmark. Bo.Thomsen@mbg.au.dk.
Matthew E WrightDepartment of Food Science & Technology, University of California, Davis, CA 95616, USA. merwright@ucdavis.edu.
Peter K TheilDepartment of Animal Science, Aarhus University, DK-8830 Tjele, Denmark. Peter.Theil@anis.au.dk.
Benjamin L SchererCommenwealth Scientific and Industrial Research Organisation (CSIRO), Biosecurity & Health, Adelaide BC, SA 5000, Australia. Ben.Scherer@csiro.au.ORCID 0000-0001-8106-381X
Maria L MarcoDepartment of Food Science & Technology, University of California, Davis, CA 95616, USA. mmarco@ucdavis.edu.
Aarhus University · DKUniversity of California, Davis · USCSIRO Health and Biosecurity · AU

Funding

Danmarks Frie Forskningsfond 4005-00258
6 · The paper itself

Abstract

High red meat intake is associated with the risk of colorectal cancer (CRC), whereas dietary fibers, such as resistant starch (RS) seemed to protect against CRC. The aim of this study was to determine whether high-amylose potato starch (HAPS), high-amylose maize starch (HAMS), and butyrylated high-amylose maize starch (HAMSB)-produced by an organocatalytic route-could oppose the negative effects of a high-protein meat diet (HPM), in terms of fermentation pattern, cecal microbial composition, and colonic biomarkers of CRC. Rats were fed a HPM diet or an HPM diet where 10% of the maize starch was substituted with either HAPS, HAMS, or HAMSB, for 4 weeks. Feces, cecum digesta, and colonic tissue were obtained for biochemical, microbial, gene expression (oncogenic microRNA), and immuno-histochemical (O

Indexed as

FermentationGastrointestinal MicrobiomeAmyloseAnimalsBiomarkers, TumorButyratesColorectal NeoplasmsDietary CarbohydratesDiet, High-ProteinIntestine, LargeMaleMicroRNAsRatsRats, Sprague-DawleySolanum tuberosumZea maysAmyloseBiomarkers, TumorButyratesDietary CarbohydratesMicroRNAsbutyratecolonDNA-adductmicrobiomemicro-RNA expressionresistant starchshort-chain fatty acids

Identifiers

PMID31052187
PMCPMC6540251
OpenAlexW2942668760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.