Evidence map›Paper›PMID 31052162›Full record

ArticleInternational journal of environmental research and public health2019

The Health Risks of Electronic Cigarette Use to Bystanders.

Wouter F Visser, Walther N Klerx, Hans W J M Cremers, Ramon Ramlal, Paul L Schwillens, Reinskje Talhout

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Exposure to Heated Tobacco Products and Adverse Health Effects, a Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Vaping and Lung Inflammation and Injury.Annual review of physiology · 2022
    Review
  10. Laboratory Determination of Gravimetric Correction Factors for Real-time Area Measurements of Electronic Cigarette Aerosols.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2022
    Article
  11. Use of E-Cigarettes and Associated Factors among Youth in Thailand.Asian Pacific journal of cancer prevention : APJCP · 2021
    Article
  12. Article
  13. 9. Flavours in novel and emerging nicotine and tobacco products.World Health Organization technical report series · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Cancer and Non-Cancer Risk Concerns from Metals in Electronic Cigarette Liquids and Aerosols.International journal of environmental research and public health · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wouter F VisserNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands. wouter.visser@rivm.nl.
Walther N KlerxNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands. walther.klerx@rivm.nl.ORCID 0000-0003-1971-2385
Hans W J M CremersNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands. hans.cremers@rivm.nl.
Ramon RamlalNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands. Ramon.ramlal@rivm.nl.
Paul L SchwillensNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands. Paul.schwillens@rivm.nl.
Reinskje TalhoutNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands. reinskje.talhout@rivm.nl.
National Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This works aimed to assess the health risks of e-cigarette use to bystanders. The exhaled breath of 17 volunteers was collected while they were vaping, and the levels of nicotine, propylene glycol, glycerol, formaldehyde, acetaldehyde, acrolein, tobacco-specific nitrosamines (TSNAs), and heavy metals were analyzed. Increased levels of nicotine, propylene glycol, TSNAs and copper were found in the exhaled breath of the volunteers. From these measurements, bystander exposure was estimated for two different scenarios: (1) A non-ventilated car with two e-cigarette users and (2) a ventilated office with one e-cigarette user. Our results show that bystanders may experience irritation of the respiratory tract as a result of exposure to propylene glycol and glycerol. Systemic effects of nicotine should also be expected if nicotine-containing e-liquid is used, including palpitations, and an increase of the systolic blood pressure. Furthermore, due to the presence of TSNAs in some e-liquids, an increased risk of tumors could not be excluded for the 'car' scenario. While e-cigarette use can clearly have effects on the health of bystanders, the risks depend on the rate of ventilation, dimensions of the room, and vaping behavior of the e-cigarette user. The presence of TSNAs in e-liquids can be avoided, which will prevent the most serious effect identified (increased risk of tumors).

Indexed as

Electronic Nicotine Delivery SystemsAdultAir Pollution, IndoorExhalationFemaleHumansMaleMiddle AgedNetherlandsRisk AssessmentVapingYoung Adultbystanderselectronic cigaretteshealth riskssecond hand vaping

Identifiers

PMID31052162
PMCPMC6539638
OpenAlexW2943334811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.