Evidence map›Paper›PMID 31052158›Full record

ArticleGenes2019

Distribution and Evolution of Nonribosomal Peptide Synthetase Gene Clusters in the

Mohammad Sayari, Magriet A van der Nest, Emma T Steenkamp, Nicole C Soal, P Markus Wilken, Brenda D Wingfield

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  9. Further Biochemical Profiling ofFrontiers in bioengineering and biotechnology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mohammad SayariDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. mohammad.sayari@fabi.up.ac.za.ORCID 0000-0001-5612-4756
Magriet A van der NestDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. magriet.vandernest@fabi.up.ac.za.
Emma T SteenkampDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. emma.steenkamp@fabi.up.ac.za.
Nicole C SoalDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. nicole.soal@fabi.up.ac.za.
P Markus WilkenDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. markus.wilken@fabi.up.ac.za.ORCID 0000-0003-0827-6098
Brenda D WingfieldDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, Pretoria 0002, South Africa. brenda.wingfield@fabi.up.ac.za.ORCID 0000-0002-6189-1519
University of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In filamentous fungi, genes in secondary metabolite biosynthetic pathways are generally clustered. In the case of those pathways involved in nonribosomal peptide production, a nonribosomal peptide synthetase (NRPS) gene is commonly found as a main element of the cluster. Large multifunctional enzymes are encoded by members of this gene family that produce a broad spectrum of bioactive compounds. In this research, we applied genome-based identification of nonribosomal peptide biosynthetic gene clusters in the family

Indexed as

Evolution, MolecularPhylogenyAscomycotaBiosynthetic PathwaysComputational BiologyMultigene FamilyPeptide SynthasesSecondary Metabolismnon-ribosomal peptide synthasePeptide SynthasesCeratocystidaceaenonribosomal peptide productionnonribosomal peptide synthetase (NRPS) genesiderophore production

Identifiers

PMID31052158
PMCPMC6563098
OpenAlexW2943486603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.