Evidence map›Paper›PMID 31050962›Full record

Observational studyJBRA assisted reproduction2019

Intrauterine insemination as a primary viable option to infertile couples: evaluation of patients in a private center.

Marília Porto Bonow, Ricardo Ditzel Delle Donne, Vinicius Bonato da Rosa, José Augusto Lucca, Cristian Maio Hillesheim, Alessandro Schuffner

Abstract readObservational Study
In one paragraph

Observational study in JBRA assisted reproduction, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marília Porto BonowGynecology and Obstetrics Post Graduation Program of Federal University of Paraná (UFPR) PR - Brazil.
Ricardo Ditzel Delle DonneGynecology and Obstetrics Post Graduation Program of Federal University of Paraná (UFPR) PR - Brazil.
Vinicius Bonato da RosaConceber Reproductive Medicine Center. Curitiba - PR - Brazil.
José Augusto LuccaConceber Reproductive Medicine Center. Curitiba - PR - Brazil.
Cristian Maio HillesheimConceber Reproductive Medicine Center. Curitiba - PR - Brazil.
Alessandro SchuffnerConceber Reproductive Medicine Center. Curitiba - PR - Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to identify which parameters positively affect the clinical pregnancy rates of IUI cycles and find which couples should opt for IUI.

methodsThis retrospective observational study included 261 patients submitted to 381 IUI cycles with fresh or cryopreserved partner semen (IU-H) from January 2012 to February 2017 in a private center in Curitiba-PR, Brazil.

resultsIdiopathic infertility was the most frequent finding (35.9%). Patients younger than 40 years accounted for 87.9% of the IUI cycles (n=335) and 16.1% of the clinical pregnancies (n=54). The pregnancy rate was three times higher in patients with an endometrium thickness ≥8 mm compared to patients with endometrium thickness <8mm. Sperm motility >55% was linked to higher pregnancy rates (p=0.002). Concerning gonadotropins, 159 (48.4%) took rFSH, 127 (38.7%) hMG, and 42 (12.8%) uFSH, with pregnancy rates of 21.3%, 10.4% and 10.5%, respectively.

conclusionPatients under 40 years of age with endometrium thickness ≥8 mm, sperm motility >55%, and on rFSH had significantly higher pregnancy rates (p<0.05).

Indexed as

InfertilityAdultFemaleFollicle Stimulating HormoneHumansInsemination, ArtificialMaleOvulation InductionPregnancyPregnancy RateRetrospective StudiesSperm MotilityFollicle Stimulating Hormoneendometrial thicknessIntrauterine inseminationrecombinant follicle stimulating hormonesperm motility.

Identifiers

PMID31050962
PMCPMC6798586

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.