Evidence map›Paper›PMID 31050928›Full record

Observational studyPhotobiomodulation, photomedicine, and laser surgery2019

Pulsed Transcranial Red/Near-Infrared Light Therapy Using Light-Emitting Diodes Improves Cerebral Blood Flow and Cognitive Function in Veterans with Chronic Traumatic Brain Injury: A Case Series.

S Gregory Hipskind, Fred L Grover, T Richard Fort, Dennis Helffenstein, Thomas J Burke, Shane A Quint, Garrett Bussiere, Michael Stone, Timothy Hurtado

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Photobiomodulation, photomedicine, and laser surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  5. Photosensitivity of an aging brain.bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

S Gregory Hipskind1 Brain Injury Consulting, LLC, Department of Brain Research, Addison, Texas.
Fred L Grover3 Revolutionary MD, Department of Medical Research, Denver, Colorado.
T Richard Fort4 CereScan Corporation, Department of Imaging Research, Littleton, Colorado.
Dennis Helffenstein5 Colorado Neuropsychological Associates, Testing Department, Englewood, Colorado.
Thomas J Burke6 University of Colorado School of Medicine, Department of Physiology (Retired), Aurora, Colorado.
Shane A Quint4 CereScan Corporation, Department of Imaging Research, Littleton, Colorado.
Garrett Bussiere4 CereScan Corporation, Department of Imaging Research, Littleton, Colorado.
Michael Stone7 Veterans Administration Hospital, Department of Radiology, Las Vegas, Nevada.
Timothy Hurtado8 Penrose-St. Francis Health Services, Emergency Department, Colorado Springs, Colorado.
Northcentral Arkansas Education Cooperative · USBrain Injury Association of America · USColorado Neurological Institute · USPenrose-St. Francis Health Services · USRevolution Research · USUnited States Department of Veterans Affairs · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Low-Level Light TherapyVeteransAdultBrain Injuries, TraumaticBrain Injury, ChronicCerebrovascular CirculationCognitionCohort StudiesHumansMaleMiddle AgedNeuropsychological TestsTomography, Emission-Computed, Single-PhotonTreatment OutcomeYoung Adultcognitive functionLEDphotobiomodulationquantitativeSPECT imagingtranscranialtraumatic brain injury

Identifiers

PMID31050928
PMCPMC6390875
OpenAlexW3012951762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.