Evidence map›Paper›PMID 31050853›Full record

ReviewJournal of neuroendocrinology2019

Development of the basal hypothalamus through anisotropic growth.

Travis Fu, Caroline Pearson, Matthew Towers, Marysia Placzek

Abstract readReview
In one paragraph

Review in Journal of neuroendocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Technologies, strategies, and cautions when deconvoluting genome-wide association signals: FTO in focus.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  4. Article
  5. Of mitogens and morphogens: modelling Sonic Hedgehog mechanisms in vertebrate development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Travis FuDepartment of Biomedical Science, Bateson Centre, University of Sheffield, Sheffield, UK.
Caroline PearsonDepartment of Biomedical Science, Bateson Centre, University of Sheffield, Sheffield, UK.
Matthew TowersDepartment of Biomedical Science, Bateson Centre, University of Sheffield, Sheffield, UK.
Marysia PlaczekDepartment of Biomedical Science, Bateson Centre, University of Sheffield, Sheffield, UK.ORCID 0000-0002-4106-9229

Funding

Wellcome Trust 156548Wellcome Trust 202756/Z/16/Z
6 · The paper itself

Abstract

The adult hypothalamus is subdivided into distinct domains: pre-optic, anterior, tuberal and mammillary. Each domain harbours an array of neurones that act together to regulate homeostasis. The embryonic origins and the development of hypothalamic neurones, however, remain enigmatic. Here, we summarise recent studies in model organisms that challenge current views of hypothalamic development, which traditionally have attempted to map adult domains to correspondingly located embryonic domains. Instead, new studies indicate that hypothalamic neurones arise from progenitor cells that undergo anisotropic growth, expanding to a greater extent than other progenitors, and grow in different dimensions. We describe in particular how a multipotent Shh

Indexed as

AnimalsFibroblast Growth Factor 10Hedgehog ProteinsHumansHypothalamusModels, NeurologicalNeural Stem CellsNeuronsFibroblast Growth Factor 10Hedgehog Proteinsanisotropic growthdevelopmentFgf10hypothalamusprechordal mesendodermprogenitorsonic hedgehog

Identifiers

PMID31050853
PMCPMC6563594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.