ReviewInternational immunology2019
Pathomechanisms of immune-mediated alopecia.
Review in International immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06946550 (1470 nm Non-Ablative Laser for the Treatment of Scarring Alopecia), which is not on this map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
1470 nm Non-Ablative Laser for the Treatment of Scarring Alopecia: A Clinical and Mechanistic Study
Who cites it
40 citing papers in PubMed, 85 citations in OpenAlex.
- Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance.Frontiers in medicine · 2026Review
- Pyroptosis in Alopecia Areata: Synthesizing Emerging Hypotheses and Charting a Path to New Therapies.Biomedicines · 2025Review
- Comparison of Current International Guidelines for the Management of Alopecia Areata-Comprehensive Review.International journal of molecular sciences · 2025Review
- Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration.Genes & diseases · 2025Review
- Article
- Cutaneous and Gut Dysbiosis in Alopecia Areata: A Review.JID innovations : skin science from molecules to population health · 2025Review
- The 100 Most-Cited Publications in Lichen Planopilaris: A Bibliometric Analysis.Skin appendage disorders · 2025Article
- Autografted hair follicles with dermal papilla removed promote wound repair and regeneration in Bama mini-pigs.Journal of molecular histology · 2025Article
- Evaluation of Olive Oil-Based Formulations Loaded with Baricitinib for Topical Treatment of Alopecia Areata.Pharmaceutics · 2025Article
- Identifying effective immune biomarkers in alopecia areata diagnosis based on machine learning methods.BMC medical informatics and decision making · 2025Article
- Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets.Frontiers in physiology · 2025Article
- From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology.Frontiers in immunology · 2025Review
- JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison.Frontiers in molecular biosciences · 2025Article
- Algae a Potential Source in Cosmetics: Current Status, Challenges, and Economic Implications.Indian journal of microbiology · 2024Review
- Advances in Topical Therapies for Clinically Relevant and Prevalent Forms of Alopecia.Life (Basel, Switzerland) · 2024Review
- Deciphering the Complex Immunopathogenesis of Alopecia Areata.International journal of molecular sciences · 2024Review
- Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration.Experimental & molecular medicine · 2024Review
- Assessing the Efficacy of Monthly 308 nm Excimer Lamp Double-Stacked Pulse Adjusted Therapy for Alopecia Areata.Skin appendage disorders · 2024Article
- Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview.Biomolecules · 2023Review
- Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
The hair follicle (HF) is a complex mini-organ that constantly undergoes dynamic cycles of growth and regression throughout life. While proper progression of the hair cycle requires homeostatic interplay between the HF and its immune microenvironment, specific parts of the HF, such as the bulge throughout the hair cycle and the bulb in the anagen phase, maintain relative immune privilege (IP). When this IP collapses, inflammatory infiltrates that aggregate around the bulge and bulb launch an immune attack on the HF, resulting in hair loss or alopecia. Alopecia areata (AA) and primary cicatricial alopecia (PCA) are two common forms of immune-mediated alopecias, and recent advancements in understanding their disease mechanisms have accelerated the discovery of novel treatments for immune-mediated alopecias, specifically AA. In this review, we highlight the pathomechanisms involved in both AA and CA in hopes that a deeper understanding of their underlying disease pathogenesis will encourage the development of more effective treatments that can target distinct disease pathways with greater specificity while minimizing adverse effects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.