ArticlePLoS genetics2019
Temporal genomic contrasts reveal rapid evolutionary responses in an alpine mammal during recent climate change.
Article in PLoS genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 89 citations in OpenAlex.
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- Unlocking natural history collections to improve eDNA reference databases and biodiversity monitoring.Bioscience · 2025Article
- Museum Genomics Reveals Temporal Genetic Stasis and Global Genetic Diversity in Arabidopsis thaliana.Molecular ecology · 2025Article
- Genetic mixing in conservation translocations increases diversity of a keystone threatened species, Bettongia lesueur.Molecular ecology · 2025Article
- A new genomic resource to enable standardized surveys of SNPs across the native range of brook trout (Salvelinus fontinalis).Molecular ecology resources · 2025Article
- Phylogenomic Analysis of Wide-Ranging Least Shrews Refines Conservation Priorities and Supports a Paradigm for Evolution of Biota Spanning Eastern North America and Mesoamerica.Ecology and evolution · 2025Article
- Polygenic response to selection by transgenic Bt-expressing crops in wild Helicoverpa zea and characterization of a major effect locus.BMC genomics · 2024Article
- Pathogen prospecting of museums: Reconstructing malaria epidemiology.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The contribution of gene flow, selection, and genetic drift to five thousand years of human allele frequency change.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Evaluating genotyping-in-thousands by sequencing as a genetic monitoring tool for a climate sentinel mammal using non-invasive and archival samples.Ecology and evolution · 2024Article
- The contribution of gene flow, selection, and genetic drift to five thousand years of human allele frequency change.bioRxiv : the preprint server for biology · 2024Article
- Arctos: Community-driven innovations for managing natural and cultural history collections.PloS one · 2024Article
- Detecting parallel polygenic adaptation to novel evolutionary pressure in wild populations: a case study in Atlantic cod (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Power of Bayesian and Heuristic Tests to Detect Cross-Species Introgression with Reference to Gene Flow in the Tamias quadrivittatus Group of North American Chipmunks.Systematic biology · 2023Article
- Sponge diversification in marine lakes: Implications for phylogeography and population genomic studies on sponges.Ecology and evolution · 2023Article
- Phylogenetic History and Phylogeographic Patterns of the European Wildcat (Animals : an open access journal from MDPI · 2023Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Many species have experienced dramatic changes in their abundance and distribution during recent climate change, but it is often unclear whether such ecological responses are accompanied by evolutionary change. We used targeted exon sequencing of 294 museum specimens (160 historic, 134 modern) to generate independent temporal genomic contrasts spanning a century of climate change (1911-2012) for two co-distributed chipmunk species: an endemic alpine specialist (Tamias alpinus) undergoing severe range contraction and a stable mid-elevation species (T. speciosus). Using a novel analytical approach, we reconstructed the demographic histories of these populations and tested for evidence of recent positive directional selection. Only the retracting species showed substantial population genetic fragmentation through time and this was coupled with positive selection and substantial shifts in allele frequencies at a gene, Alox15, involved in regulation of inflammation and response to hypoxia. However, these rapid population and gene-level responses were not detected in an analogous temporal contrast from another area where T. alpinus has also undergone severe range contraction. Collectively, these results highlight that evolutionary responses may be variable and context dependent across populations, even when they show seemingly synchronous ecological shifts. Our results demonstrate that temporal genomic contrasts can be used to detect very recent evolutionary responses within and among contemporary populations, even in the face of complex demographic changes. Given the wealth of specimens archived in natural history museums, comparative analyses of temporal population genomic data have the potential to improve our understanding of recent and ongoing evolutionary responses to rapidly changing environments.
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