Evidence map›Paper›PMID 31050388›Full record

ArticleObesity (Silver Spring, Md.)2019

Physical Activity Improves Lipid and Weight-Loss Outcomes After Metabolic Bariatric Surgery in Adolescents with Severe Obesity.

Paula Holland Price, Alexander M Kaizer, Stephen R Daniels, Todd M Jenkins, Thomas H Inge, Robert H Eckel

Registry-linked trialAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00474318 (Teen-Longitudinal Assessment of Bariatric Surgery), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00474318 completednot on this map

Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research Project

TypeobservationalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2007 to 2024Enrolled250ConditionsObesity
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Bariatric Surgery in Adolescents: To Do or Not to Do?Children (Basel, Switzerland) · 2021
    Review
  4. Article
  5. Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome.Pediatric gastroenterology, hepatology & nutrition · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Paula Holland PriceDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID 0000-0002-9928-6824
Alexander M KaizerDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.ORCID 0000-0003-2334-5514
Stephen R DanielsDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Todd M JenkinsDivision of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Thomas H IngeDepartment of Pediatric Surgery, Children's Hospital of Colorado, Aurora, Colorado, USA.
Robert H EckelDepartment of Internal Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
University of Colorado Denver · USChildren's Hospital Colorado · USCincinnati Children's Hospital Medical Center · USColorado School of Public Health · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research ProjectUM1DK072493 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI INGE, THOMAS HARRIS · 2011 to 2020
$10.5M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewalUM1DK095710 · NIDDK · UNIVERSITY OF CINCINNATI · PI JENKINS, TODD M, XIE, CHANGCHUN · 2011 to 2020
$9.4M
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral TrainingT32HL116276 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ECKEL, ROBERT H · 2014 to 2018
$1.2M
NHLBI NIH HHS T32 HL116276NIDDK NIH HHS UM1 DK072493NIDDK NIH HHS UM1 DK095710
6 · The paper itself

Abstract

objectiveThis study tested the hypothesis that physical activity improves cardiovascular disease-related lipids beyond that associated with weight loss in adolescents with severe obesity after metabolic/bariatric surgery (MBS).

methodsObjective activity monitor data from 108 participants of the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study from baseline to 3 years post MBS were used. Primary outcomes included absolute change in LDL cholesterol (LDL-C) and non-HDL cholesterol (non-HDL-C) from baseline. Baseline measurement, visit, surgical procedure, and percent change in iliac waist circumference or BMI from baseline in linear regression models were adjusted for use of generalized estimating equations. PROC TRAJ in SAS generated optimal activity trajectories based on individual step count.

resultsDespite low step counts and slow cadence, differences by activity trajectory were found. Greater absolute decreases in LDL-C and non-HDL-C (-15 mg/dL [95% CI: -28 to -2], P  = 0.026; and -15 mg/dL [95% CI: -28 to -1], P  = 0.035), respectively, were associated with more activity. More activity was associated with greater resolution of triglycerides, LDL-C, and non-HDL-C dyslipidemia and with greater weight loss 3 years post MBS.

conclusionsMore activity in adolescents was associated with improvements in cardiovascular disease-related lipid measures and weight loss after MBS.

Indexed as

AdolescentBariatric SurgeryDyslipidemiasExerciseFemaleHumansLongitudinal StudiesMaleObesity, MorbidWeight Loss

Identifiers

PMID31050388
PMCPMC6533125
OpenAlexW2943427295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.