Evidence map›Paper›PMID 31050223›Full record

ArticleJournal of Korean medical science2019

Prognostic Effect of Guideline-Directed Therapy Is More Noticeable Early in the Course of Heart Failure.

Min Soo Ahn, Byung Su Yoo, Junghan Yoon, Seung Hwan Lee, Jang Young Kim, Sung Gyun Ahn, Young Jin Youn, Jun Won Lee, Jung Woo Son, Hye Sim Kim and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Min Soo AhnDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0001-5730-8215
Byung Su YooDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea. yubs@yonsei.ac.kr.ORCID https://orcid.org/0000-0002-3395-4279
Junghan YoonDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-3363-2675
Seung Hwan LeeDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-1186-0917
Jang Young KimDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-0813-7082
Sung Gyun AhnDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-1528-2739
Young Jin YounDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0001-7066-7474
Jun Won LeeDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0001-6206-1704
Jung Woo SonDivision of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-1790-3228
Hye Sim KimCenter of Biomedical Data Science, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-7431-9722
Dae Ryong KangCenter of Biomedical Data Science, Yonsei University, Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-8792-9730
Sang Eun LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-7290-2463
Hyun Jai ChoDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-2779-4037
Hae Young LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9521-4102
Eun Seok JeonDepartment of Internal Medicine, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.ORCID https://orcid.org/0000-0002-2833-6724
Seok Min KangDepartment of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9856-9227
Dong Ju ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0003-0146-2189
Myeong Chan ChoDepartment of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-0047-0227
Wonju Severance Christian Hospital · KRSeoul National University Hospital · KRYonsei University · KRChungbuk National University Hospital · KRSamsung Medical Center · KRSeoul National University Bundang Hospital · KR

Funding

Korea Centers for Disease Control & Prevention 2010-E63003-00Korea Centers for Disease Control & Prevention 2011-E63002-00Korea Centers for Disease Control & Prevention 2012-E63005-00Korea Centers for Disease Control & Prevention 2013-E63003-00Korea Centers for Disease Control & Prevention 2013-E63003-01Korea Centers for Disease Control & Prevention 2013-E63003-02Korea Centers for Disease Control & Prevention 2016-ER6303-00
6 · The paper itself

Abstract

backgroundThere have been few studies to evaluate the prognostic implications of guideline-directed therapy according to the temporal course of heart failure. This study assessed the relationship between adherence to guideline-directed therapy at discharge and 60-day clinical outcomes in

methodsAmong 5,625 AHF patients who were recruited from a multicenter cohort registry of Korean Acute Heart Failure, 2,769 patients with reduced ejection fraction were analyzed. Guideline-directed therapies were defined as the use of angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor II blocker (ARB), β-blocker, and mineralocorticoid receptor antagonist.

resultsIn

conclusionThe prognostic implications of adherence to guideline-directed therapy at discharge were more pronounced in

Indexed as

Guideline AdherenceAcute DiseaseAdrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAtrial Natriuretic FactorCohort StudiesFemaleHeart FailureHospitalizationHumansMaleMiddle AgedMineralocorticoid Receptor AntagonistsPatient DischargeAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAtrial Natriuretic FactorMineralocorticoid Receptor AntagonistsN-terminal proatrial natriuretic peptideProtein PrecursorsAcute Decompensated Heart FailureDe Novo Acute Heart FailureGuideline-Directed Therapy

Identifiers

PMID31050223
PMCPMC6497982
OpenAlexW2941226103

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.