Evidence map›Paper›PMID 31049966›Full record

ArticleJournal of cellular physiology2019

GATA-1 isoforms differently contribute to the production and compartmentation of reactive oxygen species in the myeloid leukemia cell line K562.

Patrizia Riccio, Raffaele Sessa, Sergio de Nicola, Fara Petruzziello, Silvia Trombetti, Giuseppe Menna, Giampiero Pepe, Pasquale Maddalena, Paola Izzo, Michela Grosso

Open access · hybridAbstract read
In one paragraph

Article in Journal of cellular physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 15 citations in OpenAlex.

  1. GATA1 knockdown enhances CD8Journal of molecular histology · 2026
    Article
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  7. Review
  8. Article
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  10. Over-Expressed GATA-1Antioxidants (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Exploring the Leukemogenic Potential of GATA-1Antioxidants (Basel, Switzerland) · 2021
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Patrizia RiccioDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Raffaele SessaDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Sergio de NicolaCNR-SPIN, National Research Council, Institute for Superconductors, Innovative Materials and Devices, Naples, Italy.
Fara PetruzzielloPediatric Hematology Unit, Santobono-Pausilipon Hospital, Naples, Italy.
Silvia TrombettiDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Giuseppe MennaPediatric Hematology Unit, Santobono-Pausilipon Hospital, Naples, Italy.
Giampiero PepeCNR-SPIN, National Research Council, Institute for Superconductors, Innovative Materials and Devices, Naples, Italy.
Pasquale MaddalenaDepartment of Physics, University of Naples Federico II, Naples, Italy.
Paola IzzoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Michela GrossoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-1664-1657
University of Naples Federico II · ITSantobono Children's Hospital · ITSuperconducting and other Innovative Materials and Devices Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintenance of a balanced expression of the two isoforms of the transcription factor GATA-1, the full-length protein (GATA-1

Indexed as

Cell CompartmentationAntioxidantsApoptosisCell SurvivalCytochrome b GroupDNA, MitochondrialElectron Transport Complex IIGATA1 Transcription FactorHumansK562 CellsLeukemia, MyeloidOxidation-ReductionOxidative StressProtein IsoformsProtein SubunitsQuercetinAntioxidantscytochrome b560Cytochrome b GroupDNA, MitochondrialElectron Transport Complex IIGATA1 Transcription FactorProtein IsoformsProtein SubunitsQuercetinReactive Oxygen SpeciesSuccinate DehydrogenaseGATA-1mitochondria remodelingmyeloid leukemiaoxidative stresssuccinate dehydrogenase subunit C (SDHC)

Identifiers

PMID31049966
PMCPMC6767011
OpenAlexW2942817525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.