Evidence map›Paper›PMID 31049948›Full record

ArticleEuropean journal of immunology2019

Essential role of IκB

Sarah Frentzel, Konstantinos Katsoulis-Dimitriou, Andreas Jeron, Ingo Schmitz, Dunja Bruder

Open access · hybridAbstract read
In one paragraph

Article in European journal of immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Expression of IkappaB Family in the Ovine Liver during Early Pregnancy.Animals : an open access journal from MDPI · 2023
    Article
  2. Article
  3. Article
  4. IκBFrontiers in immunology · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah FrentzelInstitute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Konstantinos Katsoulis-DimitriouSystems-oriented Immunology and Inflammation Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Andreas JeronInstitute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Ingo SchmitzSystems-oriented Immunology and Inflammation Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.ORCID 0000-0002-5360-0419
Dunja BruderInstitute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.ORCID 0000-0003-3066-189X
Helmholtz Centre for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquisition of effector functions in T cells is guided by transcription factors, including NF-κB, that itself is tightly controlled by inhibitory proteins. The atypical NF-κB inhibitor, IκB

Indexed as

Adoptive TransferAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationCell ProliferationCytokinesI-kappa B ProteinsInterferon-gammaInterleukin-2Listeria monocytogenesListeriosisLymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutCytokinesI-kappa B ProteinsInterferon-gammaInterleukin-2NF-kappa BTumor Necrosis Factor-alphaCD4+ T cellsIn vivo infectionIκBNSListeria monocytogenesTh1 cell differentiation

Identifiers

PMID31049948
PMCPMC6771600
OpenAlexW2943788291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.