Evidence map›Paper›PMID 31049786›Full record

SynthesisCurrent oncology reports2019

The Effects of Brain Tumours upon Medical Decision-Making Capacity.

Will Hewins, Karolis Zienius, James L Rogers, Simon Kerrigan, Mark Bernstein, Robin Grant

Abstract readSystematic Review
In one paragraph

Synthesis in Current oncology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Neuro-oncology practice · 2025
    Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Will HewinsDepartment of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, Scotland.
Karolis ZieniusDepartment of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, Scotland.
James L RogersTulane University, New Orleans, LA, USA.
Simon KerriganDepartment of Neurology, Salford Royal NHS Foundation Trust, Stott Lane, Salford, M6 8HD, UK.
Mark BernsteinDivision of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Canada.
Robin GrantDepartment of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, Scotland. robin.grant@nhslothian.scot.nhs.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewInformed consent is the integral part of good medical practice in patients with brain tumours. Capacity to consent may be affected by the brain disorder or its treatment. We intend to draw upon the current neuro-oncology literature to discuss the influence intracranial tumours have upon patients' capacity to consent to treatment and research. RECENT

findingsWe performed a systematic review of studies of capacity to consent for treatment or research in patients with intracranial tumours. The search retrieved 1597 papers of which 8 were considered eligible for review. Although there are obvious inherent limitations to solely assessing cognition, most research consistently demonstrated increased risk of incapacity in brain tumour patients with cognitive impairment. Specific items in cognitive screening batteries, for example Semantic Verbal Fluency Test (SVFT), Hopkins Verbal Learning Test (HVLT-Recall), and Trail Making Test A/B (TMT), are simple, easily applied tests that may act as significant red flags to identify patients at increased risk of incapacity and who subsequently will require additional cognitive/psychiatric evaluation or more formal tests for capacity to consent for treatment or research.

Indexed as

Mental CompetencyBrain NeoplasmsCognitionCognition DisordersDecision MakingHumansInformed ConsentNeuropsychological TestsBrain metastasisBrain tumourCapacityGliomaLegal consentShared decision-making

Identifiers

PMID31049786
PMCPMC6495430

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.