Evidence map›Paper›PMID 31049758›Full record

GuidelineInternational journal of clinical oncology2019

The Japanese Lung Cancer Society Guideline for non-small cell lung cancer, stage IV.

Hiroaki Akamatsu, Kiichiro Ninomiya, Hirotsugu Kenmotsu, Masahiro Morise, Haruko Daga, Yasushi Goto, Toshiyuki Kozuki, Satoru Miura, Takaaki Sasaki, Akihiro Tamiya and 23 more

Abstract readPractice Guideline
In one paragraph

Guideline in International journal of clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Trastuzumab Deruxtecan inThe New England journal of medicine · 2022
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  16. Younger age as a risk factor for rash development in pemetrexed and carboplatin treatment with dexamethasone prophylaxis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Hiroaki AkamatsuInternal Medicine III, Wakayama Medical University, Wakayama, Japan.
Kiichiro NinomiyaDepartment of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Hirotsugu KenmotsuDivision of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Masahiro MoriseDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan.
Haruko DagaOsaka City General Hospital, Osaka, Japan.
Yasushi GotoDepartment of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.
Toshiyuki KozukiClinical Research Center, Department of Thoracic Oncology and Medicine, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Satoru MiuraDepartment of Internal Medicine, Niigata Cancer Center Hospital, Niigata, Japan.
Takaaki SasakiRespiratory Center, Asahikawa Medical University Hospital, Hokkaido, Japan.
Akihiro TamiyaNational Hospital Organization Kinki-chuo Chest Medical Center, Osaka, Japan.
Shunsuke TeraokaInternal Medicine III, Wakayama Medical University, Wakayama, Japan.
Yukari TsubataDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Shimane University Faculty of Medicine, Shimane, Japan.
Hiroshige YoshiokaDepartment of Thoracic Oncology, Kansai Medical University Hospital, Osaka, Japan.
Yoshihiro HattoriDepartment of Thoracic Oncology, Hyogo Cancer Center, Hyogo, Japan.
Chiyo K ImamuraAdvanced Cancer Translational Research Institute, Showa University, Tokyo, Japan.
Yuki KatsuyaDepartment of Surgery, University of California San Diego, California, USA.
Reiko MatsuiNational Cancer Center Hospital East, Chiba, Japan.
Yuji MinegishiDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Hidenori MizugakiFirst Department of Medicine, Hokkaido University Hospital, Hokkaido, Japan.
Kaname NosakiThoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Yusuke OkumaDepartment of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital, Tokyo, Japan.
Setsuko SakamotoKyushu University Hospital, Fukuoka, Japan.
Takashi SoneRegional Respiratory Symptomatology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.
Kentaro TanakaResearch Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Shigeki UmemuraDepartment of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.
Takeharu YamanakaDepartment of Biostatistics, Yokohama City University School of Medicine, Kanagawa, Japan.
Shinsuke AmanoJapan Federation of Cancer Patient Groups, Tokyo, Japan.
Kazuo HasegawaJapan Lung Cancer Alliance, Tokyo, Japan.
Satoshi MoritaDepartment of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kazuko NakajimaShizuoka Cancer Center, Shizuoka, Japan.
Makoto MaemondoDivision of Pulmonary Medicine, Allergry and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Iwate, Japan.
Takashi SetoThoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan. setocruise@gmail.com.
Nobuyuki YamamotoInternal Medicine III, Wakayama Medical University, Wakayama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to rapid development of chemotherapy in advanced non-small cell lung cancer (NSCLC), the Japan Lung Cancer Society has been updated its own guideline annually since 2010. In this latest version, all of the procedure was carried out in accordance with grading of recommendations assessment, development and evaluation (GRADE) system. It includes comprehensive literature search, systematic review, and determination of the recommendation by multidisciplinary expert panel which consisted of medical doctors, pharmacists, nurses, statisticians, and patients from patient advocacy group. Recently, we have had various types of chemotherapeutic drugs like kinase inhibitors or immune-checkpoint inhibitors. Thus, the guideline proposes to categorize patients into three entities: (1) driver oncogene-positive, (2) PD-L1 ≥ 50%, and (3) others. Based on this subgroup, 31 clinical questions were described. We believe that this attempt enables clinicians to choose appropriate treatment easier. Here, we report an English version of the Japan Lung Cancer Society Guidelines 2018 for NSCLC, stages IV.

Indexed as

Carcinoma, Non-Small-Cell LungHumansJapanLung NeoplasmsMedical OncologyNeoplasm GradingSocieties, MedicalChemotherapyGuidelineKinase inhibitorNon-small cell lung cancerProgramed cell death-1 inhibitorProgramed death-ligand 1 inhibitor

Identifiers

PMID31049758
PMCPMC6545178

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.