ArticleIntensive care medicine experimental2019
The physiological determinants of near-infrared spectroscopy-derived regional cerebral oxygenation in critically ill adults.
Article in Intensive care medicine experimental, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02344043 (Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness
Who cites it
14 citing papers in PubMed.
- Physiologic Determinants of Near-Infrared Spectroscopy-Derived Cerebral and Tissue Oxygen Saturation Measurements in Critically Ill Patients.Critical care explorations · 2024Trial
- Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies.Medicina (Kaunas, Lithuania) · 2026Review
- Regional Cerebral Oxygen Saturation and Risk of Delirium: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2025Review
- Evaluation of a low-cost portable NIRS device for monitoring muscle ischemia.Journal of clinical monitoring and computing · 2025Article
- Regional cerebral oxygen saturation during initial mobilization of critically ill patients is associated with clinical outcomes: a prospective observational study.Intensive care medicine experimental · 2025Article
- Near-Infrared Spectroscopy (NIRS) to Assess Infection Complications During the Acute Phase of Acute Pancreatitis.Diagnostics (Basel, Switzerland) · 2024Article
- Application of Near-Infrared Spectroscopy for the Detection of Delayed Cerebral Ischemia in Poor-Grade Subarachnoid Hemorrhage.Neurocritical care · 2021Article
- The clinical effects of cerebral near-infrared spectroscopy monitoring (NIRS) versus no monitoring: a protocol for a systematic review with meta-analysis and trial sequential analysis.Systematic reviews · 2021Article
- Individual Differences in Hemodynamic Responses Measured on the Head Due to a Long-Term Stimulation Involving Colored Light Exposure and a Cognitive Task: A SPA-fNIRS Study.Brain sciences · 2021Article
- Highlights from the Respiratory Failure and Mechanical Ventilation 2020 Conference.ERJ open research · 2021Review
- Near-Infrared Spectroscopy to Assess Cerebral Autoregulation and Optimal Mean Arterial Pressure in Patients With Hypoxic-Ischemic Brain Injury: A Prospective Multicenter Feasibility Study.Critical care explorations · 2020Article
- The Various Oximetric Techniques Used for the Evaluation of Blood Oxygenation.Sensors (Basel, Switzerland) · 2020Review
- [Diagnosing acute organ ischemia : A practical guide for the emergency and intensive care physician].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020Article
- Vasopressor Therapy and the Brain: Dark Side of the Moon.Frontiers in medicine · 2019Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundTo maintain adequate oxygen delivery to tissue, resuscitation of critically ill patients is guided by assessing surrogate markers of perfusion. As there is no direct indicator of cerebral perfusion used in routine critical care, identifying an accurate strategy to monitor brain perfusion is paramount. Near-infrared spectroscopy (NIRS) is a non-invasive technique to quantify regional cerebral oxygenation (rSO MATERIALS AND
methodsThis prospective observational study was an exploratory analysis of a nested cohort of patients within the CONFOCAL study ( NCT02344043 ) who received high-fidelity vital sign monitoring. Adult patients (≥ 18 years) admitted < 24 h to a medical/surgical intensive care unit were eligible if they had shock and/or required mechanical ventilation. Patients underwent rSO
resultsOur simultaneous multivariate model included age, heart rate, arterial oxygen saturation, mean arterial pressure, pH, partial pressure of oxygen, partial pressure of carbon dioxide (PaCO
conclusionsKnown and established physiological determinants of oxygen delivery accounted for a significant proportion of the rSO
trial registrationThis trial is registered on clinicaltrials.gov (Identifier: NCT02344043 ), retrospectively registered January 8, 2015.
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