Evidence map›Paper›PMID 31049741›Full record

ArticleLasers in medical science2020

The study of killing effect and inducing apoptosis of 630-nm laser on lung adenocarcinoma A549 cells mediated by hematoporphyrin derivatives in vitro.

Cunzhi Lin, Yuanyuan Zhang, Xinhong Zhu, Shichao Cui, Yiwei Cao, Rong Li, Lijun Wang

Abstract read
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In one paragraph

Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cunzhi LinDepartment of Respiration, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Yuanyuan ZhangDepartment of Respiration, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Xinhong ZhuDepartment of Internal Medicine, Qingdao Municipal Hospital, Qingdao, 266071, China.
Shichao CuiDepartment of Respiration, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Yiwei CaoDepartment of Respiration, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Rong LiDepartment of Respiration, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Lijun WangDepartment of Respiration, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China. 13220950371@163.com.

Funding

Huangdao Science and Technology Bureau Project of Qingdao 2014-1-77
6 · The paper itself

Abstract

To investigate the killing effect and inducing apoptosis of 630-nm laser mediated by hematoporphyrin derivatives (HPD) on human lung adenocarcinoma A549 cells. The human lung adenocarcinoma A549 cells were incubated at random with different concentrations of HPD (5, 10, 12, 15, 20 μg/ml) for 4 h and then illuminated by 630-nm laser with different energy densities (25, 50, 75, 100 mW/cm

Indexed as

ApoptosisA549 CellsAdenocarcinoma of Lungbcl-2-Associated X ProteinCaspase 3Cell ProliferationCell SurvivalDown-RegulationHematoporphyrin DerivativeHumansLasersLung NeoplasmsPhotochemotherapyPhotosensitizing AgentsRNA, MessengerSurvivinbcl-2-Associated X ProteinBIRC5 protein, humanCASP3 protein, humanCaspase 3Hematoporphyrin DerivativePhotosensitizing AgentsRNA, MessengerSurvivinA549 cellsApoptosisGene expressionHematoporphyrin derivativePhotodynamic therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.