Evidence map›Paper›PMID 31049696›Full record

ArticleParasitology research2019

Cloning, expression, characterization, and immunological properties of citrate synthase from Echinococcus granulosus.

Ning Wang, Hui Zhu, Jiafei Zhan, Cheng Guo, Nengxing Shen, Xiaobin Gu, Weimin Lai, Yue Xie, Xuerong Peng, Guangyou Yang

Abstract read
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In one paragraph

Article in Parasitology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ning WangDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Hui ZhuCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, 643000, China.
Jiafei ZhanDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Cheng GuoDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Nengxing ShenDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Xiaobin GuDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Weimin LaiDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Yue XieDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China.
Xuerong PengDepartment of Chemistry, College of Life and Basic Science, Sichuan Agricultural University, Ya'an, 625014, China.
Guangyou YangDepartment of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, 211 Huimin Road, Chengdu, 611130, Sichuan Province, China. guangyou1963@aliyun.com.
Sichuan Agricultural University · CNSichuan University of Science and Engineering · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The larval stages of the tapeworm Echinococcus granulosus (Cestoda: Taeniidae) are the causative agent of cystic echinococcosis, one of the most important parasitic zoonoses worldwide. E. granulosus has a complete pathway for the tricarboxylic acid cycle (TCA), in which citrate synthase (CS) is the key enzyme. Here, we cloned and expressed CS from E. granulosus (Eg-CS) and report its molecular characterization. The localization of this protein during different developmental stages and mRNA expression patterns during H

Indexed as

Amino Acid SequenceAnimalsAntibodiesBlotting, WesternCitrate (si)-SynthaseCitric Acid CycleCloning, MolecularCross ReactionsEchinococcosisEchinococcus granulosusEnzyme-Linked Immunosorbent AssayHydrogen PeroxideLarvaRabbitsSensitivity and SpecificitySerologic TestsAntibodiesCitrate (si)-SynthaseHydrogen PeroxideCitrate synthaseEchinococcus granulosusImmunohistochemical localizationmRNA expressionTricarboxylic acid cycle

Identifiers

PMID31049696
OpenAlexW2943482567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.