Evidence map›Paper›PMID 31049662›Full record

ArticleJournal of mathematical biology2019

The stochastic Fitzhugh-Nagumo neuron model in the excitable regime embeds a leaky integrate-and-fire model.

Marius E Yamakou, Tat Dat Tran, Luu Hoang Duc, Jürgen Jost

Abstract read
In one paragraph

Article in Journal of mathematical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Probabilistic computing with NbONature communications · 2023
    Article
  3. Article
  4. Chemical Inductor.Journal of the American Chemical Society · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marius E YamakouMax Planck Institute for Mathematics in the Sciences, Inselstraße 22, 04103, Leipzig, Germany.
Tat Dat TranMax Planck Institute for Mathematics in the Sciences, Inselstraße 22, 04103, Leipzig, Germany. trandat@mis.mpg.de.
Luu Hoang DucMax Planck Institute for Mathematics in the Sciences, Inselstraße 22, 04103, Leipzig, Germany.
Jürgen JostMax Planck Institute for Mathematics in the Sciences, Inselstraße 22, 04103, Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we provide a complete mathematical construction for a stochastic leaky-integrate-and-fire model (LIF) mimicking the interspike interval (ISI) statistics of a stochastic FitzHugh-Nagumo neuron model (FHN) in the excitable regime, where the unique fixed point is stable. Under specific types of noises, we prove that there exists a global random attractor for the stochastic FHN system. The linearization method is then applied to estimate the firing time and to derive the associated radial equation representing a LIF equation. This result confirms the previous prediction in Ditlevsen and Greenwood (J Math Biol 67(2):239-259, 2013) for the Morris-Lecar neuron model in the bistability regime consisting of a stable fixed point and a stable limit cycle.

Indexed as

Models, NeurologicalAction PotentialsAnimalsComputer SimulationNeuronsStochastic ProcessesExcitable regimeFitzHugh–Nagumo modelLeaky integrate-and-fire modelRandom attractorStationary distribution

Identifiers

PMID31049662
PMCPMC6647150

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.