ArticleNucleic acids research2019
MyDGR: a server for identification and characterization of diversity-generating retroelements.
Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- Eco-evolutionary dynamics of massive, parallel bacteriophage outbreaks in compost communities.Science advances · 2026Article
- Extensive cultivation of human gut phages revealing undescribedGut microbes · 2025Article
- Human gut strains ofApplied and environmental microbiology · 2025Article
- Zeta CrAss-like Phages, a Separate Phage Family Using a Variety of Adaptive Mechanisms to Persist in Their Hosts.International journal of molecular sciences · 2025Review
- Novel strategies for vancomycin-resistant Enterococcus faecalis biofilm control: bacteriophage (vB_EfaS_ZC1), propolis, and their combined effects in an ex vivo endodontic model.Annals of clinical microbiology and antimicrobials · 2025Article
- Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts.NPJ biofilms and microbiomes · 2025Article
- Identification of diversity-generating retroelements in host-associated and environmental genomes: prevalence, diversity, and roles.BMC genomics · 2024Article
- Genome Analysis of Epsilon CrAss-like Phages.Viruses · 2024Article
- Targeted hypermutation of putative antigen sensors in multicellular bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Ultraconserved bacteriophage genome sequence identified in 1300-year-old human palaeofaeces.Nature communications · 2024Article
- Tentaclins-A Novel Family of Phage Receptor-Binding Proteins That Can Be Hypermutated by DGR Systems.International journal of molecular sciences · 2023Article
- Knowing and Naming: Phage Annotation and Nomenclature for Phage Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Review
- A compendium of viruses from methanogenic archaea reveals their diversity and adaptations to the gut environment.Nature microbiology · 2023Article
- Broad host range may be a key to long-term persistence of bacteriophages infecting intestinal Bacteroidaceae species.Scientific reports · 2022Article
- Long-Read Metagenomics Improves the Recovery of Viral Diversity from Complex Natural Marine Samples.mSystems · 2022Article
- Identification and classification of reverse transcriptases in bacterial genomes and metagenomes.Nucleic acids research · 2022Article
- Review
- Prokaryotic reverse transcriptases: from retroelements to specialized defense systems.FEMS microbiology reviews · 2021Review
- Ecology and molecular targets of hypermutation in the global microbiome.Nature communications · 2021Article
- NovelMicroorganisms · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
MyDGR is a web server providing integrated prediction and visualization of Diversity-Generating Retroelements (DGR) systems in query nucleotide sequences. It is built upon an enhanced version of DGRscan, a tool we previously developed for identification of DGR systems. DGR systems are remarkable genetic elements that use error-prone reverse transcriptases to generate vast sequence variants in specific target genes, which have been shown to benefit their hosts (bacteria, archaea or phages). As the first web server for annotation of DGR systems, myDGR is freely available on the web at http://omics.informatics.indiana.edu/myDGR with all major browsers supported. MyDGR accepts query nucleotide sequences in FASTA format, and outputs all the important features of a predicted DGR system, including a reverse transcriptase, a template repeat and one (or more) variable repeats and their alignment featuring A-to-N (N can be C, T or G) substitutions, and VR-containing target gene(s). In addition to providing the results as text files for download, myDGR generates a visual summary of the results for users to explore the predicted DGR systems. Users can also directly access pre-calculated, putative DGR systems identified in currently available reference bacterial genomes and a few other collections of sequences (including human microbiomes).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.