Evidence map›Paper›PMID 31049457›Full record

ArticleCurrent medical mycology2019

Fatal rhinocerebral mucormycosis in a patient with ulcerative colitis receiving azathioprine and corticosteroid.

Narges Najafi, Firoozeh Kermani, Nahid Gholinejad Ghadi, Seyed Reza Aghili, Zahra Seifi, Emmanuel Roilides, Tahereh Shokohi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Current medical mycology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Colonic Mucormycosis in Fistulizing Crohn's Disease.Journal of emergencies, trauma, and shock
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Narges NajafiDepartment of Infectious Diseases, and Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Firoozeh KermaniStudent Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Nahid Gholinejad GhadiStudent Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Seyed Reza AghiliDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Zahra SeifiDepartment of Infectious Diseases, and Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Emmanuel Roilides3rd Department of Pediatrics, Infectious Diseases Section, Faculty of Medicine, Aristotle University School of Health Sciences, Thessaloniki, Greece.
Tahereh ShokohiDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mazandaran University of Medical Sciences · IRAristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeRhinocerebral mucormycosis is a rare fatal fungal infection which is on a growing trend, particularly among immunocompromised patients. Immunosuppressive drugs, including corticosteroids and antimetabolites, increase the risk of this infection. Herein, we reported the case of fulminant rhinocerebral mucormycosis in a patient with ulcerative colitis receiving azathioprine and corticosteroid. CASE REPORT: A 58-year-old woman was admitted to the hospital in a state of coma with an extensive necrosis in her nose. She was afflicted with intestinal bleeding after 1 month of fasting and was treated with azathioprine and a high dose of prednisolone for ulcerative colitis 2 months prior to hospital admission. The direct microscopic examination of the necrotic tissues of the paranasal sinuses showed several non-septate hyphae consistent with Mucorales. Culture media yielded

conclusionThe gastroenterologists should be aware of the adverse effect of immunosuppressive drugs they prescribe for the treatment of inflammatory bowel disease.

Indexed as

AzathioprineCorticosteroidInflammatory bowel diseaseMucormycosisRhinocerebralUlcerative colitis

Identifiers

PMID31049457
PMCPMC6488282
OpenAlexW2932921441

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.