ArticleCurrent medical mycology2019
Detection of ERG11 point mutations in Iranian fluconazole-resistant
Article in Current medical mycology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
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- Sequential Induction of Drug Resistance and Characterization of an InitialJournal of fungi (Basel, Switzerland) · 2024Article
- Antifungal activity of three different varieties of Capsicum annuum against clinical isolates of Candida species.Tropical diseases, travel medicine and vaccines · 2023Article
- Analysis of molecular resistance to azole and echinocandin inCurrent medical mycology · 2022Article
- Molecular typing of multi-drug resistant Candida albicans isolated from the Segamat community, Malaysia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- The effects of secreted aspartyl proteinase inhibitor ritonavir on azoles-resistant strains of Candida albicans as well as regulatory role of SAP2 and ERG11.Immunity, inflammation and disease · 2021Article
- Antifungal Activity of Curcuminoids and Difluorinated Curcumin Against Clinical Isolates of Candida Species.Advances in experimental medicine and biology · 2021Article
- The A756T Mutation of theFrontiers in veterinary science · 2021Article
- Detection of antifungal drug-resistant andF1000Research · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeCandidiasis is referred to a group of superficial and deep-tissue fungal infections often caused by MATERIALS AND
methodsThis study was conducted on a total of 216 clinical isolates obtained from Mashhad, Isfahan, and Tehran cities in Iran, during 2016-2018. The clinical isolates were identified using molecular techniques. Furthermore, minimum inhibitory concentration (MICs) was determined according to the clinical and laboratory standards institute M27-A3 and M27-S4 documents. The concentration range for fluconazole was obtained as 0.063-64 μg/ml. In the resistant strains,
resultsOut of 216 strains, 100 (46.3%) species were identified as
conclusionFluconazole resistance among clinical isolates is not merely due to the changes in ERG11p. This resistance may be also related to some other mechanisms, such as the prevention of the intracellular accumulation of the antifungal agent and alteration of the target enzyme to diminish drug binding.
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Registered trials
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