Evidence map›Paper›PMID 31049414›Full record

ArticleBJGP open2019

Effectiveness of delivering integrated COPD care at public healthcare facilities: a cluster randomised trial in Pakistan.

Muhammad Amir Khan, Nida Khan, John D Walley, Muhammad Ahmar Khan, Joseph Hicks, Maqsood Ahmed, Faisal Imtiaz Sheikh, Muhammad Ali, Farooq Manzoor, Haroon Jehangir Khan

Abstract read
In one paragraph

Article in BJGP open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Integrated care for chronic respiratory disease: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad Amir KhanChief Coordinating Professional, Association for Social Development, Islamabad, Pakistan.
Nida KhanProject Coordinator, Association for Social Development, Islamabad, Pakistan.
John D WalleyProfessor of International Public Health, Nuffield Centre for International Health and Development, University of Leeds, Leeds, UK.
Muhammad Ahmar KhanResearch Coordinator, Association for Social Development, Islamabad, Pakistan.
Joseph HicksSenior Medical Statistician, Nuffield Centre for International Health and Development, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Maqsood AhmedSenior Professional, Association for Social Development, Islamabad, Pakistan.
Faisal Imtiaz SheikhResearch Coordinator, Association for Social Development, Islamabad, Pakistan.
Muhammad AliResearch Assistant, Association for Social Development, Islamabad, Pakistan.
Farooq ManzoorProvincial Manager, Non-Communicable Disease Control Program, Directorate General of Health Services, Punjab, Pakistan.
Haroon Jehangir KhanDirector, NCD & Mental Health, Directorate General of Health Services, Punjab, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Pakistan chronic obstructive pulmonary disease (COPD) prevalence is 2.1% in adults aged >40 years. Despite being a health policy focus, integrated COPD care has remained neglected, with wide variation in practice.

aimTo assess whether enhanced care at public health facilities resulted in better control of COPD, treatment adherence, and smoking cessation. DESIGN &

settingA two-arm cluster randomised controlled trial was undertaken in 30 public health facilities (23 primary and 7 secondary), across three districts of Punjab, between October 2014-December 2016. Both arms had enhanced diagnosis and patient recording processes. Intervention facilities also had clinical care guides; drugs for COPD; patient education flipcharts; associated staff training; and mobile phone follow-up.

methodFacilities were randomised in a 1:1 ratio (sealed envelope independent lottery method), and 159 intervention and 154 control patients were recruited. The eligibility criteria were as follows: diagnosed with COPD, aged ≥18 years, and living in the catchment area. The primary outcome was change in BODE (Body mass index, airway Obstruction, Dyspnoea, Exercise capacity) index score from baseline to final follow-up visit. Staff and patients were not blinded.

resultsSix-month primary outcomes were available for 147/159 (92.5%) intervention and 141/154 (91.6%) control participants (all clusters). The primary outcome results cluster-level analysis were as follows: mean intervention outcome = -1.67 (95% confidence intervals [CI] = -2.18 to -1.16); mean control outcome = -0.66 (95% CI = -1.09 to -0.22); and covariate-adjusted mean intervention-control difference = -0.96 (95% CI = -1.49 to -0.44;

conclusionThe findings of this trial and a separate process evaluation study support the scaling of this integrated COPD care package at primary and secondary level public health facilities in Pakistan and similar settings.

Indexed as

COPDgeneral practiceintegrated care packagePakistanprimary carepublic health facilities

Identifiers

PMID31049414
PMCPMC6480856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.