Evidence map›Paper›PMID 31049358›Full record

ArticleJournal of immunology research2019

Genetic Predisposition to Hepatocarcinogenesis in Inbred and Outbred Mouse Lines Selected for High or Low Inflammatory Response.

Lilian Rego de Carvalho, Andrea Borrego, José Ricardo Jensen, Wafa Hanna Koury Cabrera, Aline Marques Santos, Orlando Garcia Ribeiro, Nancy Starobinas, Marcelo De Franco, Tommaso A Dragani, Giacomo Manenti and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Lilian Rego de CarvalhoLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.
Andrea BorregoLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0001-6454-9279
José Ricardo JensenLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0001-6228-2988
Wafa Hanna Koury CabreraLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0003-1973-4664
Aline Marques SantosDepartment of Pathology, University of Brasilia, Brasilia, Brazil.
Orlando Garcia RibeiroLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0003-2117-2402
Nancy StarobinasLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0001-5716-3394
Marcelo De FrancoLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0002-0417-8215
Tommaso A DraganiDepartment of Predictive and Preventive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Giacomo ManentiDepartment of Predictive and Preventive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Olga Célia Martinez IbañezLaboratory of Immunogenetics, Instituto Butantan, São Paulo, Brazil.ORCID 0000-0002-2672-4758
Instituto Butantan · BRFondazione IRCCS Istituto Nazionale dei Tumori · ITUniversidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIRmax and AIRmin mouse strains phenotypically selected for high and low acute inflammatory responsiveness (AIR) are, respectively, susceptible or resistant to developing hepatocellular carcinoma (HCC) induced by the chemical carcinogens urethane and diethylnitrosamine (DEN). Early production of TNF-

Indexed as

Animals, Outbred StrainsGenetic Predisposition to DiseaseAllelesAnimalsCarcinogenesisCarcinoma, HepatocellularDisease Models, AnimalGenetic LinkageInbreedingInflammationInterleukin-1betaInterleukin-6Liver NeoplasmsMiceMice, Inbred C57BLPhenotypeIL1B protein, mouseInterleukin-1betaInterleukin-6interleukin-6, mouseTumor Necrosis Factors

Identifiers

PMID31049358
PMCPMC6462334
OpenAlexW2934087742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.