Evidence map›Paper›PMID 31049286›Full record

ArticlePhotoacoustics2019

Photoacoustic-based oxygen saturation assessment of murine femoral bone marrow in a preclinical model of leukemia.

Cayla Wood, Karine Harutyunyan, Diego R T Sampaio, Marina Konopleva, Richard Bouchard

Open access · goldAbstract read
In one paragraph

Article in Photoacoustics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Visualizing Vascular Bone Marrow Niche Alterations in Diabetes.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Cayla WoodDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Karine HarutyunyanDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Diego R T SampaioDepartment of Physics, University of Sao Paulo, Ribeirao Preto, SP, Brazil.
Marina KonoplevaDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Richard BouchardDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
The University of Texas MD Anderson Cancer Center · USUniversidade de São Paulo · BR

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Targeting hypoxic microenvironment in Acute Lymphocytic LeukemiaR01CA155056 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONOPLEVA, MARINA Y · 2011 to 2015
$1.6M
iThera Medical Multispectral Optoacoustic Tomography System for Full Body Molecular and Functional Small Animal ImagingS10OD019946 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SOKOLOV, KONSTANTIN V · 2015 to 2015
$502k
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA155056NIH HHS S10 OD019946
6 · The paper itself

Abstract

A variety of hematological diseases manifest in the bone marrow (BM), broadly characterized as BM failure (BMF). BMF can be caused by acute lymphoblastic leukemia (ALL), which results in an expansion of hypoxic regions in the BM. Because of this hypoxic presentation, there is potential for improved characterization of BMF through

Indexed as

Acute lymphoblastic leukemiaBone marrowPhotoacoustic imagingPreclinical imagingSO2 estimation

Identifiers

PMID31049286
PMCPMC6484208
OpenAlexW2917730412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.