Evidence map›Paper›PMID 31049235›Full record

ArticleCase reports in oncological medicine2019

Electrochemotherapy as Promising Treatment Option in Rare Recurrent Cutaneous Neoplasm of the Scalp: Case Report of an Elderly Patient.

Edoardo Crimini, Michela Roberto, Valter Degli Effetti, Paolo Marchetti, Andrea Botticelli, Francesca Matilde Schipilliti, Giulia Arrivi, Federica Mazzuca

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PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Edoardo CriminiMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Michela RobertoMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-5339-8348
Valter Degli EffettiPlastic Surgery Unit, Paideia Clinic, Rome, Italy.
Paolo MarchettiMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Andrea BotticelliMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-6425-9893
Francesca Matilde SchipillitiMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Giulia ArriviMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Federica MazzucaMedical Oncology Unit, S Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtypical fibroxanthoma (AFX) is a tumor that commonly presents on the head or neck in older individuals. Making a definitive diagnosis of AFX is challenging, and frequently, it is hard to distinguish from pleomorphic dermal sarcoma (PDS). There are no clear recommendations regarding the treatment of AFX, but an extensive surgery is actually considered the best option. Electrochemotherapy (ECT) is a novel therapeutic modality of local treatment in which the application of electrical pulses, enhancing cell membrane permeability, allows greater intracellular accumulation of chemotherapy drugs in the skin or subcutaneous tumors. CASE REPORT: We report a case of a 78-year-old male affected by a red, ulcerative, dermal, scalp nodule, which was treated with ECT with a complete clinical response. We have also reported literature data on this topic.

resultsIn this case, ECT showed to be an effective and safe treatment for recurrent neoplasms of the head and neck, considering the complete response obtained and the absence of disease relapse after two years.

conclusionTo the best of our knowledge, this is the first case report that shows great clinical results using ECT after surgery in relapsed AFX/PDS. However, more studies are needed to confirm our results.

Identifiers

PMID31049235
PMCPMC6458881
OpenAlexW2933862445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.