Evidence map›Paper›PMID 31049124›Full record

ArticleOxidative medicine and cellular longevity2019

2-Allylphenol Reduces IL-1

Humberto de Carvalho Aragão Neto, Diogo Vilar da Fonsêca, Renan Marinho Braga, Marcus Tullius Scotti, Terezinha Weyne Araújo Borges do Nascimento, Davidson Barbosa Assis, Sandra Rodrigues-Mascarenhas, Luiz Henrique Agra Cavalcante Silva, José Guilherme Ferreira Marques Galvão, Hugo Alexandre Oliveira Rocha and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Involvement of GABABioMed research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Humberto de Carvalho Aragão NetoInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.ORCID 0000-0002-2264-2966
Diogo Vilar da FonsêcaInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.
Renan Marinho BragaInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.
Marcus Tullius ScottiInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.ORCID 0000-0003-4863-8057
Terezinha Weyne Araújo Borges do NascimentoInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.
Davidson Barbosa AssisInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.
Sandra Rodrigues-MascarenhasInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.ORCID 0000-0003-4192-7382
Luiz Henrique Agra Cavalcante SilvaInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.ORCID 0000-0002-8445-5189
José Guilherme Ferreira Marques GalvãoInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.
Hugo Alexandre Oliveira RochaDepartment of Biochemistry, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil.ORCID 0000-0003-2252-1221
Arthur Antunes Jacome VidalDepartment of Biochemistry, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil.
José Maria Barbosa FilhoInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.ORCID 0000-0002-9567-4096
Reinaldo Nóbrega de AlmeidaInstitute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa 58051-085, Brazil.ORCID 0000-0003-4430-8202
Universidade Federal da Paraíba · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2-Allylphenol (2-AP) is a synthetic phenylpropanoid, structurally related to cardanol, thymol, and ortho-eugenol. Phenylpropanoids are described in the literature as being capable of promoting biological activity. Due to the similarity between 2-AP and other bioactive phenylpropanoids, the present research aims at evaluating the antioxidant, antinociceptive, and anti-inflammatory potential of 2-AP in silico,

Indexed as

AnalgesicsAnimalsAnti-Inflammatory AgentsAntioxidantsInterleukin-1betaMaleMiceMolecular Docking SimulationPeritonitisPhenolsReceptor, Adenosine A2ATumor Necrosis Factor-alpha2-allylphenolAdora2a protein, mouseAnalgesicsAnti-Inflammatory AgentsAntioxidantsIL1B protein, mouseInterleukin-1betaPhenolsReceptor, Adenosine A2ATumor Necrosis Factor-alpha

Identifiers

PMID31049124
PMCPMC6462329
OpenAlexW2931164805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.