ArticleNeural plasticity2019
Motor Control Deficits in Facial Synkinesis Patients: Neuroimaging Evidences of Cerebral Cortex Involvement.
Article in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Geometric Microstructural Characteristics of White Matter Differentiate Patients With Facial Dyskinesias and Palsy.CNS neuroscience & therapeutics · 2026Article
- Beyond motor recovery: emerging perspectives in the management of peripheral facial palsy-a narrative review.Frontiers in neurology · 2026Review
- Sensorimotor regulation of facial expression - An untouched frontier.Neuroscience and biobehavioral reviews · 2024Review
- Combining early lower eyelid surgery with neuromuscular retraining for synkinesis prevention after facial palsy: the role of the eye in aberrant facial nerve regeneration.Frontiers in neurology · 2024Article
- Deficits of Visual Cortex Function in Acute Acquired Concomitant Esotropia Patients.Investigative ophthalmology & visual science · 2023Article
- Identifying Modulated Functional Connectivity in Corresponding Cerebral Networks in Facial Nerve Lesions Patients With Facial Asymmetry.Frontiers in neuroscience · 2022Article
- Structural remodeling in related brain regions in patients with facial synkinesis.Neural regeneration research · 2021Article
- Alteration of spatial patterns at the network-level in facial synkinesis: an independent component and connectome analysis.Annals of translational medicine · 2021Article
- Article
- Structural remodeling secondary to functional remodeling in advanced-stage peripheral facial neuritis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Intra and inter: Alterations in functional brain resting-state networks after peripheral nerve injury.Brain and behavior · 2020Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: Facial synkinesis is a severe sequelae of facial nerve malfunction. Once the synkinesis is established, it is extremely difficult for patients to recover. Given that the restoration of motor or sensory function after peripheral nerve injury was closely related with cortical plasticity, we investigated cortical plasticity in facial synkinesis patients by the frequency-specific data which remains largely uncharacterized. Materials and Methods: Resting-state fMRI was conducted in 20 facial synkinesis patients and 19 healthy controls, and the amplitude of low-frequency fluctuation (ALFF) in five different frequency bands (slow-6: 0-0.01 Hz; slow-5: 0.01-0.027 Hz; slow-4: 0.027-0.073 Hz; slow-3: 0.073-0.167 Hz; and slow-2: 0.167-0.25 Hz) was calculated, respectively. And the relationship between ALFF and clinical outcomes was also analyzed. Results: Comparing with the healthy controls, facial synkinesis patients showed significantly different ALFF values, mainly in the sensorimotor areas. Furthermore, increased ALFF of the ipsilateral insula in the slow-6 band was significantly related with better facial nerve function. Conclusion: Increased ALFF values in the ipsilateral insula might reflect an abnormal state of hypercompensation in motor control of facial synkinesis patients. It provided valuable spatial information about the functionally aberrant regions, which implied the possible involvement of motor control system in facial synkinesis.
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