Evidence map›Paper›PMID 31049024›Full record

ArticleMediators of inflammation2019

Cytotoxic Function and Cytokine Production of Natural Killer Cells and Natural Killer T-Like Cells in Systemic Lupus Erythematosis Regulation with Interleukin-15.

Syh-Jae Lin, Ming-Ling Kuo, Hsiu-Shan Hsiao, Pei-Tzu Lee, Wen-I Lee, Ji-Yih Chen, Jing-Long Huang

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Sulfated Polysaccharides ofFood science & nutrition · 2025
    Article
  8. The Role of Killer Ig-like Receptors in Diseases from A to Z.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. The role of CD56Journal of neuroinflammation · 2024
    Review
  13. Article
  14. [Interferon-α mediating the functional damage of CD56Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  15. Increased ILT2Clinical rheumatology · 2023
    Article
  16. Natural Killer T-like Cells: Immunobiology and Role in Disease.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Syh-Jae LinDepartment of Pediatrics, Division of Asthma, Allergy, and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0001-7689-0650
Ming-Ling KuoDepartment of Pediatrics, Division of Asthma, Allergy, and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0003-1959-4972
Hsiu-Shan HsiaoDepartment of Pediatrics, Division of Asthma, Allergy, and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Pei-Tzu LeeDepartment of Pediatrics, Division of Asthma, Allergy, and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wen-I LeeDepartment of Pediatrics, Division of Asthma, Allergy, and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0003-2683-3169
Ji-Yih ChenDepartment of Medicine, Division of Allergy, Immunology and Rheumatology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan, Taiwan.ORCID 0000-0001-5661-6291
Jing-Long HuangDepartment of Pediatrics, Division of Asthma, Allergy, and Rheumatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0002-3530-7753
Chang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer cells and NKT-like cells are the first line immune defense against tumor and virus infection. Deficient NK and NKT-like cell effector function may contribute to increased susceptibility to infection in SLE patients. We sought to examine the perforin and granzyme B expression, interferon-gamma (IFN-

Indexed as

AdultAgedCells, CulturedCytokinesFemaleGranzymesHumansInterferon-gammaInterleukin-15Killer Cells, NaturalLupus Erythematosus, SystemicMaleMiddle AgedPerforinTumor Necrosis Factor-alphaCytokinesGranzymesInterferon-gammaInterleukin-15PerforinTumor Necrosis Factor-alpha

Identifiers

PMID31049024
PMCPMC6462338
OpenAlexW2931000830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.