ArticleGenetics in medicine : official journal of the American College of Medical Genetics2019
The current state of funded NIH grants in implementation science in genomic medicine: a portfolio analysis.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- An analysis of National Cancer Institute-funded scale-up research.Frontiers in health services · 2025Pooled it
- What is the power of a genomic multidisciplinary team approach? A systematic review of implementation and sustainability.European journal of human genetics : EJHG · 2024Pooled it
- A multilevel adaptation approach for the sustainable scale-up of family cancer history screening in rural public health clinics.Archives of public health = Archives belges de sante publique · 2026Article
- Article
- A guide to utilizing implementation science for genetic counseling.Journal of genetic counseling · 2025Article
- Protocol for a type 3 hybrid implementation cluster randomized clinical trial to evaluate the effect of patient and clinician nudges to advance the use of genomic medicine across a diverse health system.Implementation science : IS · 2024Article
- Navigating the field of implementation science towards maturity: challenges and opportunities.Implementation science : IS · 2024Article
- Evaluating cancer genetic services in a safety net system: overcoming barriers for a lasting impact beyond the CHARM research project.Journal of community genetics · 2023Article
- Precision medicine in Australia: now is the time to get it right.The Medical journal of Australia · 2022Article
- Using a Participatory Approach to Develop Research Priorities for Future Leaders in Cancer-Related Precision Public Health.Frontiers in genetics · 2022Article
- Behavioral and Psychological Outcomes Associated with Skin Cancer Genetic Testing in Albuquerque Primary Care.Cancers · 2021Article
- Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network.Journal of personalized medicine · 2021Article
- A scoping review of social and behavioral science research to translate genomic discoveries into population health impact.Translational behavioral medicine · 2021Article
- Future directions for implementation science at the National Cancer Institute: Implementation Science Centers in Cancer Control.Translational behavioral medicine · 2021Article
- Availability and funding of clinical genomic sequencing globally.BMJ global health · 2021Review
- Systemic Barriers to Risk-Reducing Interventions for Hereditary Cancer Syndromes: Implications for Health Care Inequities.JCO precision oncology · 2021Review
- Applying theory to characterize impediments to dissemination of community-facing family health history tools: a review of the literature.Journal of community genetics · 2020Review
- Opportunities, challenges and expectations management for translating biobank research to precision medicine.European journal of epidemiology · 2020Article
- Building the Next Generation of Implementation Science Careers to Advance Health Equity.Ethnicity & disease · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeImplementation science offers methods to evaluate the translation of genomic medicine research into practice. The extent to which the National Institutes of Health (NIH) human genomics grant portfolio includes implementation science is unknown. This brief report's objective is to describe recently funded implementation science studies in genomic medicine in the NIH grant portfolio, and identify remaining gaps.
methodsWe identified investigator-initiated NIH research grants on implementation science in genomic medicine (funding initiated 2012-2016). A codebook was adapted from the literature, three authors coded grants, and descriptive statistics were calculated for each code.
resultsForty-two grants fit the inclusion criteria (~1.75% of investigator-initiated genomics grants). The majority of included grants proposed qualitative and/or quantitative methods with cross-sectional study designs, and described clinical settings and primarily white, non-Hispanic study populations. Most grants were in oncology and examined genetic testing for risk assessment. Finally, grants lacked the use of implementation science frameworks, and most examined uptake of genomic medicine and/or assessed patient-centeredness.
conclusionWe identified large gaps in implementation science studies in genomic medicine in the funded NIH portfolio over the past 5 years. To move the genomics field forward, investigator-initiated research grants should employ rigorous implementation science methods within diverse settings and populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.