Evidence map›Paper›PMID 31048785›Full record

ArticleScientific reports2019

Amelioration of obesity-related biomarkers by Lactobacillus sakei CJLS03 in a high-fat diet-induced obese murine model.

Yosep Ji, Soyoung Park, Youngmee Chung, Bobae Kim, Haryung Park, Eunchong Huang, Dahye Jeong, Hoe-Yune Jung, Bongjoon Kim, Chang-Kee Hyun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. The anti-obesity effects ofApplied and environmental microbiology · 2025
    Article
  7. Journal of agricultural and food chemistry · 2025
    Article
  8. Review
  9. DietaryFrontiers in microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. International journal of molecular sciences · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. International journal of molecular sciences · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yosep JiAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea.ORCID http://orcid.org/0000-0001-5349-7901
Soyoung ParkAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea.
Youngmee ChungCJ Blossom Park, 42, Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16495, Republic of Korea.
Bobae KimAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea.ORCID http://orcid.org/0000-0003-1624-8337
Haryung ParkAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea.
Eunchong HuangAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea.ORCID http://orcid.org/0000-0003-3760-6164
Dahye JeongCJ Blossom Park, 42, Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16495, Republic of Korea.
Hoe-Yune JungDepartment of Life Science, Division of Integrative Biosciences and Biotechnology, POSTECH, Pohang, Gyungbuk, 37673, Republic of Korea.
Bongjoon KimCJ Blossom Park, 42, Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16495, Republic of Korea.
Chang-Kee HyunAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea.ORCID http://orcid.org/0000-0003-1862-8739
Wilhelm H HolzapfelAdvanced Green Energy and Environment, Handong Global University, Pohang, Gyungbuk, 37554, Republic of Korea. wilhelm@woodapple.net.ORCID http://orcid.org/0000-0002-3669-1419
Handong Global University · KRCJ CheilJedang (South Korea) · KRPohang University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent progresses in clinical diagnostic analyses have demonstrated the decisive influence of host gut microbiota on the status of metabolic disorders. Short chain fatty acids (SCFAs) produced by gut microbiota, in particular, are considered as a key biomarker, both of communication between gut microbiota and the host, and of impact on host metabolic homeostasis. Microbiota modulation and concomitant anti-obesity effects of probiotics have been reported by different researchers. However, the underlying modulatory functions of probiotics on gut microbiota towards host metabolic homeostasis are still not fully understood. In this study, the impact of Lactobacillus sakei CJLS03 (isolated from Korean kimchi) on obesity-related biomarkers was investigated using a diet-induced obese mouse model. Body weight increase, SCFAs, the gut microbiota and various obesity-associated biomarkers were significantly and beneficially influenced by L. sakei CJLS03 administration compared to the control groups. Analytical data on faecal samples support the role of the colonic microbial population in SCFA production. The composition of the latter may be influenced by modulation of the distal gastro-intestinal microbiota by putative probiotics such as L. sakei CJLS03.

Indexed as

BiomarkersDiet, High-FatGastrointestinal MicrobiomeLatilactobacillus sakeiAdipocytesAdipose TissueAnimalsDisease Models, AnimalFatty Acids, VolatileMiceMice, ObeseObesityWeight GainBiomarkersFatty Acids, Volatile

Identifiers

PMID31048785
PMCPMC6497927
OpenAlexW2943182465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.