ReviewMedical science monitor : international medical journal of experimental and clinical research2019
Postoperative Cognitive Decline After Cardiac Surgery: A Narrative Review of Current Knowledge in 2019.
Review in Medical science monitor : international medical journal of experimental and clinical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 6 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Unraveling the impact of frailty on postoperative delirium in elderly surgical patients: a systematic review and meta-analysis.BMC anesthesiology · 2025Pooled it
- Effect of esketamine on postoperative delirium in general anesthesia patients undergoing elective surgery: a meta-analysis of randomized controlled trials.BMC anesthesiology · 2024Pooled it
- Cognitive dysfunction in older patients undergoing non-neurosurgery in the immediate postoperative period: A systematic review.Nursing open · 2024Pooled it
- Outcomes associated with postoperative cognitive dysfunction: a systematic review and meta-analysis.Age and ageing · 2024Pooled it
- Electroencephalography Monitoring for Preventing Postoperative Delirium and Postoperative Cognitive Decline in Patients Undergoing Cardiothoracic Surgery: A Meta-Analysis.Reviews in cardiovascular medicine · 2024Pooled it
- Effectiveness of cognitive interventions for adult surgical patients after general anaesthesia to improve cognitive functioning: A systematic review.Journal of clinical nursing · 2023Pooled it
- Overtime work of anesthesiologists is associated with increased delirium in older patients admitted to intensive care unit after noncardiac surgery: a secondary analysis.BMC anesthesiology · 2024Trial
- Effects of Remimazolam on Intraoperative Frontal Alpha Band Power Spectrum Density and Postoperative Cognitive Function in Older Adults Undergoing Lower Extremity Fractures Surgeries: A Randomized Controlled Trial.Clinical interventions in aging · 2024Trial
- Intranasal Dexmedetomidine-Esketamine Combination Premedication versus Monotherapy for Reducing Emergence Delirium and Postoperative Behavioral Changes in Pediatric Tonsillectomy and/or Adenoidectomy: A Randomized Controlled Trial.Drug design, development and therapy · 2024Trial
- Longitudinal assessment of preoperative dexamethasone administration on cognitive function after cardiac surgery: a 4-year follow-up of a randomized controlled trial.BMC anesthesiology · 2021Trial
- Effects of Transcutaneous Electrical Acupoint Stimulation on Postoperative Cognitive Decline in Elderly Patients: A Pilot Study.Clinical interventions in aging · 2021Trial
- Comparison of postoperative delirium within 24 hours between ketamine and propofol infusion during cardiopulmonary bypass machine: A randomized controlled trial.Annals of cardiac anaesthesiaTrial
- Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia.Healthcare (Basel, Switzerland) · 2026Review
- From heart to mind: A narrative review of incidence, risk factors, and mechanisms of dementia after cardiac surgery.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- In-hospital coded prevalence and associated factors of postoperative delirium following rotator cuff repair surgery: a retrospective national inpatient sample database study.Perioperative medicine (London, England) · 2026Article
- Analysis of Determinants and Development of a Predictive Model for Postoperative Cognitive Dysfunction in Patients Undergoing Hepatectomy.Journal of clinical medicine · 2026Article
- Transcranial doppler assessment of preoperative cerebral blood flow velocity in cardiac surgery patients.Journal of clinical monitoring and computing · 2026Observational
- Morin improves postoperative cognitive dysfunction by mediating the miR-138-5p/SIRT1 axis to regulate ferroptosis.Scientific reports · 2026Article
- Early Postoperative Cognitive Performance After Total Arch Replacement: A Prospective Observational Study.Anesthesiology research and practice · 2026Article
- A prospective cohort study on the incidence and influencing factors of subsyndromal delirium in ICU patients.Frontiers in psychiatry · 2026Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The growing number of publications concerning postoperative cognitive decline (POCD) after cardiac surgery is indicative of the health-related and economic-related importance of this intriguing issue. Significantly, the reported POCD incidence over the years has remained steady due to various unresolved challenges regarding the examination of this multidisciplinary topic. In particular, a universally accepted POCD definition has not been established, and the pathogenesis is still vaguely understood. However, numerous recent studies have focused on the role of the inflammatory response to a surgical procedure in POCD occurrence. Therefore, this traditional narrative review summarizes and evaluates the latest findings, with special attention paid to the difficulties of defining POCD as well as the involvement of inflammation in POCD development. We searched the MEDLINE, Scopus, PsycINFO and CENTRAL databases for the best evidence, which was classified according to the Oxford Centre for Evidence-based Medicine. To our knowledge, this is the first narrative review that identified class-1 evidence (systematic review of randomized trials), although most evidence is still at class-2 or below. Furthermore, we revealed that defining POCD is a very controversial matter and that the inflammatory response plays an important role in the mutually overlapping processes included in POCD development. Thus, developing the definition of POCD represents an absolute priority in POCD investigations, and the inflammatory response to cardiac surgery merits further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.