Evidence map›Paper›PMID 31048453›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2019

Quantifying Hepatic Enzyme Kinetics of (-)-∆

Gabriela I Patilea-Vrana, Jashvant D Unadkat

Open access · bronzeAbstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. UGT2B7-mediated drug-drug interaction between cannabinoids and hydromorphone.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
  6. Article
  7. Article
  8. Are ΔInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Characterizing and Quantifying Extrahepatic Metabolism of (-)-ΔDrug metabolism and disposition: the biological fate of chemicals · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Development and Verification of a LinkedDrug metabolism and disposition: the biological fate of chemicals · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gabriela I Patilea-VranaDepartment of Pharmaceutics, University of Washington, Seattle, Washington.ORCID 0000-0002-5795-0547
Jashvant D UnadkatDepartment of Pharmaceutics, University of Washington, Seattle, Washington jash@uw.edu.
University of Washington · US

Funding

Pharmacology CoreU54AT008909 · NCCIH · WASHINGTON STATE UNIVERSITY · PI BOYCE, RICHARD DAVID · 2015 to 2024
$22.4M
Understanding Fetal Exposure to Cannabinoids Through In Vitro and In Vivo StudiesP01DA032507 · NIDA · UNIVERSITY OF WASHINGTON · PI UNADKAT, JASHVANT D · 2013 to 2023
$12.4M
NCCIH NIH HHS U54 AT008909NIDA NIH HHS P01 DA032507
6 · The paper itself

Abstract

The prevalence of cannabis use and the concentrations of the psychoactive cannabinoid in cannabis, (-)-∆

Indexed as

Cytochrome P-450 CYP3ADronabinolDrug InteractionsGlucuronosyltransferaseHumansIn Vitro TechniquesMicrosomes, Liver11-hydroxy-delta(9)-tetrahydrocannabinolCYP3A4 protein, humanCytochrome P-450 CYP3ADronabinolGlucuronosyltransferase

Identifiers

PMID31048453
PMCPMC6556521
OpenAlexW2942812716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.