Evidence map›Paper›PMID 31048429›Full record

ArticleBMJ open2019

Challenges and opportunities for involving patients and the public in acute antimicrobial medicine development research: an interview study.

Andy Gibson, Michele Kok, David Evans, Sally Grier, Alasdair MacGowan

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. The Development of Principles for Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: A Modified Delphi Study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  4. Article
  5. Perspectives of researchers and clinicians on patient and public involvement (PPI) in preclinical spinal cord research: An interview study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  6. Article
  7. Applying Patient and Public Involvement in preclinical research: A co-created scoping review.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andy GibsonDepartment of Health and Social Sciences, University of West England, Bristol, UK.
Michele KokDepartment of Health and Social Sciences, University of West England, Bristol, UK.
David EvansDepartment of Health and Social Sciences, University of West England, Bristol, UK.
Sally GrierDepartment of Infection Sciences, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
Alasdair MacGowanDepartment of Infection Sciences, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore what approaches to patient and public involvement (PPI) in antimicrobial medicines development are currently being used, what the impacts of PPI are on antimicrobial medicines development and what the barriers are to its implementation.

designInterview study.

settingAntimicrobial medicines development research.

participantsPrincipal investigators known to have led studies involving PPI or expressed an interest in PPI.

resultsThere is very little published work on PPI in antimicrobial research. Individual interviewees expressed scepticism about the contribution that PPI could make to different stages of the medicines development life cycle but collectively identified a range of potential benefits of PPI covering most stages of the medicines development process.

conclusionsA major issue in developing PPI in antimicrobial medicines development research will be in overcoming the view that, at best, PPI has only a marginal contribution to make in this area of research. The findings from this study, although mixed, suggest that well-designed PPI has an untapped potential to enhance antimicrobial research.

Indexed as

Drug DesignPatient ParticipationAnti-Bacterial AgentsCooperative BehaviorDrug Resistance, MicrobialHumansInterviews as TopicPublic OpinionQualitative ResearchResearch DesignAnti-Bacterial Agentsacute infectionsantimicrobial researchchallenges and opportunitiespatient and public involvement

Identifiers

PMID31048429
PMCPMC6501967

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.