Evidence map›Paper›PMID 31048300›Full record

ArticleAJNR. American journal of neuroradiology2019

Dynamic Contrast-Enhanced MRI to Differentiate Parotid Neoplasms Using Golden-Angle Radial Sparse Parallel Imaging.

J L Mogen, K T Block, N K Bansal, J T Patrie, S Mukherjee, E Zan, M Hagiwara, G M Fatterpekar, S H Patel

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

J L MogenFrom the Department of Radiology (J.L.M.), Tufts Medical Center, Boston, Massachusetts.ORCID 0000-0002-1258-8038
K T BlockDepartment of Radiology (K.T.B., N.K.B., E.Z., M.H., G.M.F.), New York University Langone Medical Center, New York, New York.ORCID 0000-0003-3426-965X
N K BansalDepartment of Radiology (K.T.B., N.K.B., E.Z., M.H., G.M.F.), New York University Langone Medical Center, New York, New York.ORCID 0000-0003-0273-6954
J T PatrieDivision of Biostatistics and Epidemiology (J.T.P.), University of Virginia, Charlottesville, Virginia.ORCID 0000-0001-7392-830X
S MukherjeeDepartment of Radiology and Medical Imaging (S.M., S.H.P.), University of Virginia Health System, Charlottesville, Virginia.ORCID 0000-0001-6031-2557
E ZanFrom the Department of Radiology (J.L.M.), Tufts Medical Center, Boston, Massachusetts.ORCID 0000-0003-0941-1466
M HagiwaraDepartment of Radiology (K.T.B., N.K.B., E.Z., M.H., G.M.F.), New York University Langone Medical Center, New York, New York.ORCID 0000-0002-3715-5159
G M FatterpekarDepartment of Radiology (K.T.B., N.K.B., E.Z., M.H., G.M.F.), New York University Langone Medical Center, New York, New York.ORCID 0000-0002-4705-2030
S H PatelDepartment of Radiology and Medical Imaging (S.M., S.H.P.), University of Virginia Health System, Charlottesville, Virginia. shp4@virginia.edu.ORCID 0000-0002-9739-4362
NYU Langone Health · USTufts Medical Center · USUniversity of Virginia Health System · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeConventional imaging frequently shows overlapping features between benign and malignant parotid neoplasms. We investigated dynamic contrast-enhanced MR imaging using golden-angle radial sparse parallel imaging in differentiating parotid neoplasms. MATERIALS AND

methodsFor this retrospective study, 41 consecutive parotid neoplasms were imaged with dynamic contrast-enhanced MR imaging with golden-angle radial sparse parallel imaging using 1-mm in-plane resolution. The temporal resolution was 3.4 seconds for 78.2 seconds and 8.8 seconds for the remaining acquisition. Three readers retrospectively and independently created and classified time-intensity curves as follows: 1) continuous wash-in; 2) rapid wash-in, subsequent plateau; and 3) rapid wash-in with washout. Additionally, time-intensity curve-derived semiquantitative metrics normalized to the ipsilateral common carotid artery were recorded. Diagnostic performance for the prediction of neoplasm type and malignancy was assessed. Subset multivariate analysis (

resultsIndependent time-intensity curve classification of the 41 neoplasms produced moderate-to-substantial interreader agreement (κ = 0.50-0.79). The time-intensity curve classification threshold of ≥2 predicted malignancy with a positive predictive value of 56.0%-66.7%, and a negative predictive value of 92.0%-100%. The time-intensity curve classification threshold of <2 predicted pleomorphic adenoma with a positive predictive value of 87.0%-95.0% and a negative predictive value of 76.0%-95.0%. For all readers, type 2 and 3 curves were associated with malignant neoplasms (

conclusionsGolden-angle radial sparse parallel MR imaging allows high spatial and temporal resolution permeability characterization of parotid neoplasms, with a high negative predictive value for malignancy prediction. Combining time-to-maximum and ADC improves pleomorphic adenoma prediction compared with either metric alone.

Indexed as

AdultAgedAged, 80 and overContrast MediaFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedParotid NeoplasmsRetrospective StudiesContrast Media

Identifiers

PMID31048300
PMCPMC7028581
OpenAlexW2942677935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.