Evidence map›Paper›PMID 31048295›Full record

ArticleAJNR. American journal of neuroradiology2019

Lumbar Spinal Stenosis Severity by CT or MRI Does Not Predict Response to Epidural Corticosteroid versus Lidocaine Injections.

F A Perez, S Quinet, J G Jarvik, Q T Nguyen, E Aghayev, D Jitjai, W D Hwang, E R Jarvik, S S Nedeljkovic, A L Avins and 9 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

F A PerezFrom the Department of Radiology (F.A.P., J.G.J., Q.T.N., D.H.).ORCID 0000-0001-8456-5209
S QuinetDepartment of Radiology (S.Q.), College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0002-7231-9788
J G JarvikFrom the Department of Radiology (F.A.P., J.G.J., Q.T.N., D.H.).ORCID 0000-0002-0528-3455
Q T NguyenFrom the Department of Radiology (F.A.P., J.G.J., Q.T.N., D.H.).ORCID 0000-0002-2693-3672
E AghayevSpinal Centre Division (E.A.), Schulthess Klinik, Zurich, Switzerland.ORCID 0000-0002-7032-8218
D JitjaiOregon Health Sciences University (D.J.) Portland, Oregon.ORCID 0000-0002-3760-5391
W D HwangTRA Medical Imaging (W.D.H.), Tacoma, Washington.ORCID 0000-0003-0525-4512
E R JarvikUniversity of Washington Medicine (E.R.J.), Seattle, Washington.ORCID 0000-0003-3727-2336
S S NedeljkovicDepartment of Anesthesiology, Perioperative and Pain Medicine and Spine Unit (S.S.N.), Harvard Vanguard Medical Associates, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0001-9795-3155
A L AvinsDivision of Research (A.L.A.), Kaiser Permanente Northern California, Oakland, California.ORCID 0000-0003-1723-7904
J M SchwalbDepartment of Neurosurgery (J.M.S., D.R.N.), Henry Ford Medical Group, Detroit, Michigan.ORCID 0000-0002-8714-161X
F E DiehnDepartment of Radiology (F.E.D.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-9458-8017
C J StandaertDepartment of Physical Medicine and Rehabilitation (C.J.S.), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.ORCID 0000-0001-6808-355X
D R NerenzDepartment of Neurosurgery (J.M.S., D.R.N.), Henry Ford Medical Group, Detroit, Michigan.ORCID 0000-0002-5050-5950
T AnnaswamyDepartment of Physical Medicine and Rehabilitation (T.A.), VA North Texas Healthcare System, Dallas, Texas.ORCID 0000-0002-3969-9221
Z BauerCancer and Blood Disorders Center (Z.B.), Seattle Children's Research Institute, Seattle, Washington.ORCID 0000-0002-9860-5846
D HaynorFrom the Department of Radiology (F.A.P., J.G.J., Q.T.N., D.H.).ORCID 0000-0002-8940-7426
P J HeagertyComparative Effectiveness, Cost and Outcomes Research Center (J.G.J., P.J.H., J.L.F.).ORCID 0000-0002-3851-2664
J L FriedlyComparative Effectiveness, Cost and Outcomes Research Center (J.G.J., P.J.H., J.L.F.) friedlyj@uw.edu.ORCID 0000-0002-7483-7888

Funding

Back pain Outcomes using Longitudinal Data (BOLD)R01HS019222 · AHRQ · UNIVERSITY OF WASHINGTON · PI JARVIK, JEFFREY G · 2010 to 2010
$9.9M
Back pain Outcomes using Longitudinal Data- Extension of Research (BOLDER)R01HS022972 · AHRQ · UNIVERSITY OF WASHINGTON · PI JARVIK, JEFFREY G · 2013 to 2013
$741k
AHRQ HHS R01 HS019222AHRQ HHS R01 HS022972
6 · The paper itself

Abstract

background and purposeEpidural steroid injections may offer little-to-no short-term benefit in the overall population of patients with symptomatic spinal stenosis compared with lidocaine alone. We investigated whether imaging could identify subgroups of patients who might benefit most. MATERIALS AND

methodsA secondary analysis of the Lumbar Epidural Steroid Injections for Spinal Stenosis prospective, double-blind trial was performed, and patients were randomized to receive an epidural injection of lidocaine with or without corticosteroids. Patients (

resultsThere was no difference in the improvement of disability or leg pain scores at 3 weeks between patients injected with epidural lidocaine alone compared with corticosteroid and lidocaine when accounting for the primary imaging measures of qualitative spinal stenosis assessment (interaction coefficients for disability score, -0.1; 95% CI, -1.3 to 1.2;

conclusionsImaging measures of spinal stenosis are not associated with differential clinical responses following epidural corticosteroid injection.

Indexed as

Treatment OutcomeAdrenal Cortex HormonesAdultAgedAnesthetics, LocalAnti-Inflammatory AgentsDouble-Blind MethodDrug Therapy, CombinationFemaleHumansInjections, EpiduralLidocaineLumbar VertebraeMagnetic Resonance ImagingMaleMiddle AgedAdrenal Cortex HormonesAnesthetics, LocalAnti-Inflammatory AgentsLidocaine

Identifiers

PMID31048295
PMCPMC7053900

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.