Evidence map›Paper›PMID 31047891›Full record

ReviewNeuroscience and biobehavioral reviews2019

Motivation and cognitive control in depression.

Ivan Grahek, Amitai Shenhav, Sebastian Musslick, Ruth M Krebs, Ernst H W Koster

Registry-linked trialAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05936697 (Neurofeedback Training to Improve Prefrontal Functioning in Older Adults With Subclinical Depression and Anxiety), which is not on this map. Cited by 162 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05936697 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Neurofeedback Training to Improve Prefrontal Functioning in Older Adults With Subclinical Depression and Anxiety: a Randomised Control Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2023 to 2024Enrolled90ConditionsDepression, AnxietyArmsfNIRS, EEG, Baseline Training
3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
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  9. The neuroanatomy of depression: weak but replicable effects in 4021 individuals from three clinical cohorts.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  15. On the Limitations of Burnout as an Indicator of Job-Related Distress.Annals of the New York Academy of Sciences · 2026
    Review
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102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ivan GrahekDepartment of Experimental Clinical and Health Psychology, Ghent University, Henri Dunantlaan 2, B-9000, Ghent, Belgium. Electronic address: ivan.grahek@ugent.be.
Amitai ShenhavDepartment of Cognitive, Linguistic, & Psychological Science and Brown Institute for Brain Science, Brown University, Providence, RI, 02912, USA.
Sebastian MusslickPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, 07001, USA.
Ruth M KrebsDepartment of Experimental Psychology, Ghent University, Henri Dunantlaan 2, B-9000, Ghent, Belgium.
Ernst H W KosterDepartment of Experimental Clinical and Health Psychology, Ghent University, Henri Dunantlaan 2, B-9000, Ghent, Belgium.

Funding

The neural basis of sequential control in human and non-human primatesP20GM103645 · NIGMS · BROWN UNIVERSITY · PI WORDEN, MICHAEL S · 2013 to 2022
$22.9M
NIGMS NIH HHS P20 GM103645
6 · The paper itself

Abstract

Depression is linked to deficits in cognitive control and a host of other cognitive impairments arise as a consequence of these deficits. Despite of their important role in depression, there are no mechanistic models of cognitive control deficits in depression. In this paper we propose how these deficits can emerge from the interaction between motivational and cognitive processes. We review depression-related impairments in key components of motivation along with new cognitive neuroscience models that focus on the role of motivation in the decision-making about cognitive control allocation. Based on this review we propose a unifying framework which connects motivational and cognitive control deficits in depression. This framework is rooted in computational models of cognitive control and offers a mechanistic understanding of cognitive control deficits in depression.

Indexed as

Models, BiologicalRewardAnhedoniaCognitive DysfunctionDecision MakingDepressive DisorderExecutive FunctionHumansMotivationAnhedoniaCognitive controlControllability of environmentDepressionEffortMotivationReward anticipation

Identifiers

PMID31047891
PMCPMC6642074

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.