ArticleOphthalmology. Retina2018
Telemedical Diagnosis of Stage 4 and Stage 5 Retinopathy of Prematurity.
Article in Ophthalmology. Retina, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Risk factors and efficacy of different intravitreal treatment options for symptomatic focal vitreomacular traction with or without full-thickness macular hole.International ophthalmology · 2025Article
- Quantitative evaluation of the wide-field fundus photographs in eyes with severe stage 3 and stage 4A retinopathy of prematurity.BMC ophthalmology · 2025Article
- Cost-effectiveness of Artificial Intelligence-Based Retinopathy of Prematurity Screening.JAMA ophthalmology · 2022Article
- Telemedicine in ophthalmology in view of the emerging COVID-19 outbreak.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Review
- Developing a pediatric ophthalmology telemedicine program in the COVID-19 crisis.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2020Article
- Aggressive Posterior Retinopathy of Prematurity: Clinical and Quantitative Imaging Features in a Large North American Cohort.Ophthalmology · 2020Article
- Multimodal Imaging, Tele-Education, and Telemedicine in Retinopathy of Prematurity.Middle East African journal of ophthalmologyReview
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo determine the accuracy of image-based diagnosis for stage 4 or worse retinopathy of prematurity (ROP) disease.
designProspective cohort study.
participantsWe prospectively obtained data, from 8 major ROP centers, for 1220 eye examinations from 230 infants.
methodsAn ophthalmologist at each center provided a clinical diagnosis using indirect ophthalmoscopy. Wide-angle retinal images (RetCam; Clarity Medical Systems, Pleasanton, CA) were then obtained, and these were independently read by 2 ROP experts using a web-based system for an image-based diagnosis.
main outcome measuresSensitivity and specificity of image-based diagnosis from the ROP experts were calculated using the clinical diagnosis as the reference standard.
resultsOf 1220 examinations, 28 (2%) had a clinical diagnosis of stage 4 or worse. Sensitivity and specificity for stage 4 or worse disease were 75% and 99% for expert 1, and 86% and 99% for expert 2. Sensitivity and specificity for the detection of stage 5 disease were 69% and 99% for both experts.
conclusionsThere are inconsistencies in the accuracy of image-based diagnosis of stage 4 and stage 5 ROP when compared with the clinical diagnosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.