ArticleBMC evolutionary biology2019
Rapid functional divergence after small-scale gene duplication in grasses.
Article in BMC evolutionary biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 33 citations in OpenAlex.
- A sorghum-anchored pan-grass syntenic gene set in grasses.NAR genomics and bioinformatics · 2026Article
- Evolutionary dynamics and functional diversification of BBX transcription factors in CFrontiers in plant science · 2025Article
- Comparative analysis of IRE1s in plants: insights into heat stress adaptation in Triticum aestivum.BMC plant biology · 2024Article
- Characteristics of duplicated gene expression and DNA methylation regulation in different tissues of allopolyploid Brassica napus.BMC plant biology · 2024Article
- Predicting evolutionary targets and parameters of gene deletion from expression data.Bioinformatics advances · 2024Article
- DNA methylation signatures of duplicate gene evolution in angiosperms.Plant physiology · 2023Article
- Predicting gene expression divergence between single-copy orthologs in two species.Genome biology and evolution · 2023Article
- Comparative gene retention analysis in barley, wild emmer, and bread wheat pangenome lines reveals factors affecting gene retention following gene duplication.BMC biology · 2023Article
- Genetic Redundancy in Rye Shows in a Variety of Ways.Plants (Basel, Switzerland) · 2023Review
- Cell wall integrity regulation across plant species.Plant molecular biology · 2022Review
- The origin and evolution of a two-component system of paralogous genes encoding the centromeric histone CENH3 in cereals.BMC plant biology · 2021Article
- Article
- Expression of Two Rye CENH3 Variants and Their Loading into Centromeres.Plants (Basel, Switzerland) · 2021Article
- Article
- BLAST from the Past: Impacts of Evolving Approaches on Studies of Evolution by Gene Duplication.Genome biology and evolution · 2021Article
- A co-opted steroid synthesis gene, maintained in sorghum but not maize, is associated with a divergence in leaf wax chemistry.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Learning Retention Mechanisms and Evolutionary Parameters of Duplicate Genes from Their Expression Data.Molecular biology and evolution · 2021Article
- NAC and MYB Families and Lignin Biosynthesis-Related Members Identification and Expression Analysis inPlants (Basel, Switzerland) · 2021Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGene duplication has played an important role in the evolution and domestication of flowering plants. Yet little is known about how plant duplicate genes evolve and are retained over long timescales, particularly those arising from small-scale duplication (SSD) rather than whole-genome duplication (WGD) events.
resultsWe address this question in the Poaceae (grass) family by analyzing gene expression data from nine tissues of Brachypodium distachyon, Oryza sativa japonica (rice), and Sorghum bicolor (sorghum). Consistent with theoretical predictions, expression profiles of most grass genes are conserved after SSD, suggesting that functional conservation is the primary outcome of SSD in grasses. However, we also uncover support for widespread functional divergence, much of which occurs asymmetrically via the process of neofunctionalization. Moreover, neofunctionalization preferentially targets younger (child) duplicate gene copies, is associated with RNA-mediated duplication, and occurs quickly after duplication. Further analysis reveals that functional divergence of SSD-derived genes is positively correlated with both sequence divergence and tissue specificity in all three grass species, and particularly with anther expression in B. distachyon.
conclusionsOur results suggest that SSD-derived grass genes often undergo rapid functional divergence that may be driven by natural selection on male-specific phenotypes. These observations are consistent with those in several animal species, suggesting that duplicate genes take similar evolutionary trajectories in plants and animals.
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