Evidence map›Paper›PMID 31046536›Full record

ArticleAmerican journal of men's health

The Impacts of Ramadan Intermittent Fasting on Oxidant/Antioxidant Stress Biomarkers of Stable Chronic Obstructive Pulmonary Disease Male Patients.

Sawssan Mrad, Hadhemi Rejeb, Jihene Ben Abdallah, Hajer Graiet, Mouna Ben Khelifa, Amel Abed, Salima Ferchichi, Khelifa Limem, Helmi Ben Saad

Open access · goldAbstract read
In one paragraph

Article in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
  7. The effect of Ramadan fasting on nasal mucociliary activity and peak nasal inspiratory flow.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sawssan Mrad1 Laboratory of Biochemistry, Farhat Hached Hospital, Sousse, Tunisia.
Hadhemi Rejeb2 Pulmonary Department, Farhat Hached Hospital, Sousse, Tunisia.
Jihene Ben Abdallah1 Laboratory of Biochemistry, Farhat Hached Hospital, Sousse, Tunisia.
Hajer Graiet3 Research Unit of Clinical and Molecular Biology (UR17ES29), University of Monastir, Tunisia.ORCID 0000-0002-5274-5325
Mouna Ben Khelifa2 Pulmonary Department, Farhat Hached Hospital, Sousse, Tunisia.
Amel Abed1 Laboratory of Biochemistry, Farhat Hached Hospital, Sousse, Tunisia.
Salima Ferchichi3 Research Unit of Clinical and Molecular Biology (UR17ES29), University of Monastir, Tunisia.
Khelifa Limem1 Laboratory of Biochemistry, Farhat Hached Hospital, Sousse, Tunisia.
Helmi Ben Saad4 Laboratory of Physiology and Functional Explorations, Farhat Hached Hospital, Sousse, Tunisia.ORCID 0000-0002-7477-2965
Hôpital Farhat Hached · TNUniversity of Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

No prior study has evaluated the impacts of Ramadan intermittent fasting (RIF) on oxidant/antioxidant stress (OS/AOS) biomarkers in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to assess the impacts of RIF on some OS/AOS biomarkers measured in male patients with stable COPD. Fifteen COPD patients (mean age: 71 ± 6 years) fasting Ramadan in 2017 volunteered to take part in the study. Three sessions (before Ramadan [BR], end Ramadan [ER], after Ramadan [AR]) were selected. Blood samples of OS (homocysteine [μmol/L], thiobarbituric acid reactive substances [TBARS, μmol/L]) and AOS (catalase [U/ml], ceruloplasmin [g/L], superoxide dismutase [SOD, ng/ml], zinc [µmol/L], albumin [g/L]) biomarkers were consistently taken 4.5 to 2.5 hr before the iftar. Findings were analyzed by applying Friedman or Kruskal-Wallis ANOVA. Comparisons of the number of patients with high OS [high homocysteine and/or TBARS] and low AOS (low catalase and/or ceruloplasmin and/or SOD and/or zinc and/or albumin) blood values between the three sessions were performed using the Cochran test. The median ± interquartile of homocysteine (BR: 21.48 [18.98-24.49], ER: 23.15 [21.77-26.45], AR: 24.87 [21.91-37.12]), ceruloplasmin (BR: 0.27 [0.24-0.30], ER: 0.28 [0.26-0.33], AR: 0.28 [0.25-0.32]), SOD (BR: 288.00 [112.00-400.00], ER: 182.00 [152.00-386.00], AR: 234.00 [190.00-420.00]) and the mean ± SD of TBARS (BR: 5.66 ± 1.26, ER: 4.59 ± 0.78, AR: 5.29 ± 1.69), catalase (BR: 120.97 ± 54.62, ER: 106.73 ± 50.92, AR: 137.39 ± 40.88), zinc (BR: 11.85 ± 2.01, ER: 12.47 ± 2.34, AR: 12.21 ± 2.58) and albumin (BR: 39.78 ± 3.19, ER: 40.74 ± 2.26, AR: 40.56 ± 2.38) were not significantly affected by RIF. The number of patients with high OS (BR [ n = 13], ER [ n = 15], AR [ n = 14]) or low AOS (BR [ n = 12], ER [ n = 13], AR [ n = 13]) statuses were not significantly influenced by RIF. In conclusion, RIF did not induce any significant statistical or clinical changes in OS/AOS biomarkers or statuses in COPD patients.

Indexed as

FastingIslamAgedAntioxidantsBiomarkersCatalaseCeruloplasminHomocysteineHumansMaleOxidantsPulmonary Disease, Chronic ObstructiveSampling StudiesSerum AlbuminSuperoxide DismutaseThiobarbituric Acid Reactive SubstancesAntioxidantsBiomarkersCatalaseCeruloplasminHomocysteineOxidantsSerum AlbuminSuperoxide DismutaseThiobarbituric Acid Reactive SubstancesZincbalance oxidant/antioxidantfeastingoxidative stress statusrespiratory diseases

Identifiers

PMID31046536
PMCPMC6501488
OpenAlexW2943751255

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.