ArticleJournal of the American Heart Association2019
Incidence and Clinical Impact of Recurrent Takotsubo Syndrome: Results From the GEIST Registry.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed, 132 citations in OpenAlex.
- Apical-to-Mid-Ventricular Phenotypic Shift in Recurrent Takotsubo Syndrome After Minor Trauma.JACC. Case reports · 2026Article
- Neuroimaging biomarkers of the brain-heart axis in Takotsubo syndrome: regional convergence without directional consistency: a systematic review and biomarker qualification appraisal.Acta neurologica Belgica · 2026Review
- A Rare Case of Takotsubo Cardiomyopathy Recurrence With Alternate Reverse Phenotypes.The American journal of case reports · 2026Article
- Article
- Recurrence of Takotsubo Syndrome: Incidence and Clinical Characteristics.Circulation reports · 2026Article
- Physical triggers in takotsubo syndrome: a high-risk phenotype? insights from the eVOLUTION registry.European heart journal. Cardiovascular Imaging · 2026Observational
- Prognostic Value of Hepatic T1 Mapping in Patients with Takotsubo Syndrome.Journal of clinical medicine · 2026Article
- Takotsubo Syndrome: The First Non-Acute Proteomic Analysis by Remote Dried Blood Microsampling.Journal of cardiovascular translational research · 2026Article
- Heart Transplantation from Donors with Takotsubo Cardiomyopathy: Clinical Outcomes and Early Experience from a Single Center.Journal of clinical medicine · 2026Article
- Multimodality Imaging in the Diagnosis of an Early Tako-Tsubo Syndrome Recurrence.Diagnostics (Basel, Switzerland) · 2026Article
- Rare Case of Second Recurrence of Takotsubo Cardiomyopathy With Variable Ballooning Pattern.The American journal of case reports · 2026Article
- The Shape-Shifting Heart: Recurrent Takotsubo Cardiomyopathy Manifesting as Two Variants in One Patient.Cureus · 2026Article
- Takotsubo Syndrome in 2025: Evolving Concepts in Pathophysiology, Diagnosis, and Long-Term Management.Journal of clinical medicine · 2025Review
- Takotsubo Cardiomyopathy: An Exploration of the Intersection Between Stress, Coronary Dysfunction, and Cardiac Outcomes.Reviews in cardiovascular medicine · 2025Review
- Neurological complications in Takotsubo syndrome: A case of concurrent acute stroke.Global cardiology science & practice · 2025Article
- Heart-Brain axis: is microvascular dysfunction the link between stroke and Takotsubo syndrome?The international journal of cardiovascular imaging · 2025Review
- Long-Term Prognosis, Risk Assessment, and Management of Patients Diagnosed with Takotsubo Syndrome: A Narrative Review.Journal of personalized medicine · 2025Review
- Recurrent Takotsubo Cardiomyopathy With Variable Patterns and Psychiatric Comorbidities: A Case Report and Comprehensive Literature Review.Clinical case reports · 2025Article
- Serotonin Norepinephrine Reuptake Inhibitor Is Associated With Lower Mortality Among Patients Presenting With Takotsubo Cardiomyopathy.Journal of the American Heart Association · 2025Article
- Pregnancy-Associated Takotsubo Syndrome: A Narrative Review of the Literature.Journal of clinical medicine · 2025Review
13 more citing papers are in PubMed but not listed here.
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Authors and funding
17 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Current literature only reports variable information from single-center studies on the recurrence rate, the complications, and the outcome of patients with Takotsubo syndrome ( TTS) experiencing recurrent TTS . Therefore, a detailed description of clinical characteristics, predictors, and the prognostic impact of patients with TTS and recurrences in a multicenter registry is needed. Methods and Results We analyzed 749 patients with TTS from 9 European centers being part of the international, multicenter GEIST (German Italian Stress Cardiomyopathy) Registry. Patients were divided into the recurrence group and the nonrecurrence group. The recurrence rate at a median follow-up of 830 days (interquartile range, 118-1701 days) was 4%. Most recurrences were documented in the first 5 years after the index TTS episode. Up to 2 TTS recurrences were documented in 2 of 30 patients (6%). A variable ballooning pattern (n=6, 0.8%) with, in particular, involvement of the right ventricular occurred in 3 cases (0.4%) at the recurrence event. Except for the higher presence of arterial hypertension (86.7% versus 68.3%; P=0.03) in the recurrence group, no other baseline characteristics were different between groups. Observation of TTS complications during follow-up, including stroke, thromboembolic events, in-hospital death, and cardiogenic shock, revealed no significant differences between groups ( P>0.05), except the higher presence of pulmonary edema in the recurrence group versus the nonrecurrence group (13.3% versus 4.9%; P=0.04). Conclusions The incidence of TTS recurrence is estimated to be 4% in this multicenter TTS registry. A variable TTS pattern at recurrence is common in up to 20% of recurrence cases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.