Evidence map›Paper›PMID 31046065›Full record

Trial reportJAMA oncology2019

Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer.

Bram De Laere, Prabhakar Rajan, Henrik Grönberg, Luc Dirix, Johan Lindberg, CORE-ARV-CTC and ProBIO Investigators

Erratum issuedAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in JAMA oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Heterogeneity of [European journal of nuclear medicine and molecular imaging · 2023
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  14. Error in the Figure.JAMA oncology · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Bram De LaereDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Prabhakar RajanCentre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
Henrik GrönbergDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Luc DirixCenter for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium.
Johan LindbergDepartment of Medical Epidemiology and Biostatistics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.
CORE-ARV-CTC and ProBIO Investigators

Funding

Cancer Research UK 15339
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overAndrostenesAntineoplastic AgentsBenzamidesBiomarkers, TumorHumansMaleNitrilesPhenylthiohydantoinProstatic Neoplasms, Castration-ResistantProtein IsoformsReceptors, AndrogenTreatment OutcomeTumor Suppressor Protein p53abirateroneAndrostenesAntineoplastic AgentsAR protein, humanBenzamidesBiomarkers, TumorenzalutamideNitrilesPhenylthiohydantoinProtein IsoformsReceptors, AndrogenTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID31046065
PMCPMC6499126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.