Evidence map›Paper›PMID 31045844›Full record

Observational studyMedicine2019

Retrospective observational analysis of hospital discharge database to characterize primary pulmonary hypertension and its outcomes in Spain from 2004 to 2015.

Javier de-Miguel-Díez, Ana Lopez-de-Andres, Valentin Hernandez-Barrera, Isabel Jimenez-Trujillo, Manuel Mendez-Bailon, Jose M de Miguel-Yanes, Nuria Muñoz-Rivas, Martin Romero-Maroto, Rodrigo Jimenez-Garcia

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Javier de-Miguel-DíezRespiratory Department, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid (UCM), Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM).
Ana Lopez-de-AndresPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón.
Valentin Hernandez-BarreraPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón.
Isabel Jimenez-TrujilloPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón.
Manuel Mendez-BailonInternal Medicine Department. Hospital Universitario Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid.
Jose M de Miguel-YanesInternal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Facultad de Medicina, Universidad Complutense de Madrid (UCM).
Nuria Muñoz-RivasInternal Medicine Department, Hospital Universitario Infanta Leonor, Madrid, Spain.
Martin Romero-MarotoPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón.
Rodrigo Jimenez-GarciaPreventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine trends in the incidence, characteristics and outcomes, and to identify factors associated with in-hospital mortality (IHM) of patients hospitalized for primary pulmonary hypertension (PPH) in Spain (2004-2015).We included all patients hospitalized with PPH and included in the Spanish National Hospital Discharge Database.We analyzed 46,883 discharges of patients (7.14% with PPH as their primary diagnosis). Incidence rates decreased from 6.15 cases per 100,000 inhabitants in 2004-06 to 3.40 in 2013-15 (P < .001). Mean age rose from 66.43 ± 21.28 to 69.73 ± 21.12 years (P < .001) and the proportion of females increased over the study period (58.44% vs 60.71%; P < .001). Comorbidity using the Charlson Comorbidity Index (CCI) also increased with 16.07% having CCI ≥3 in 2004-06 vs 21.795 in 2013-15. Median length of hospital stay (LOHS) was 1 day longer in period 2004-06, than in 2013-15 (9 vs 8 days; P < .001). The proportion of patients who were considered a readmission and the mean costs increased from 15.7% and 3712.46&OV0556; in the first period to 17.14% and 4040.28&OV0556; in 2013-15 (P < .001). IHM increased from 8.2% in 2004-06 to 9.93% in 2013-15 (P < .001). The predictors' of IHM among PPH patients included comorbidity and use of mechanical ventilation. Primary diagnosis of PPH did not predict higher IHM (OR 1.07; 95%CI 09-1.26).Our data indicates that the incidence of hospitalizations decreased in Spain between 2004 and 2015. Parallel, LOHS also decreased during this period. By contrast, comorbidity increased over time in PPH patients, as well as readmission rates, costs and IHM.

Indexed as

AgedDatabases, FactualFamilial Primary Pulmonary HypertensionFemaleHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedOutcome Assessment, Health CarePatient DischargeRetrospective StudiesSpain

Identifiers

PMID31045844
PMCPMC6504269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.